Morphological and Ancillary Features of Uterine Leiomyosarcoma: Case Report.
We report a rare case of giant uterine leiomyosarcoma in a postmenopausal woman, whose diagnosis was initially suspected at the evaluation of the abdominal efusion, and confirmed after the pathological examination of the uterus in association with the ancillary tests. The evaluation of the abdominal...
| Publicado en: | Clinical Pathology Vol. 15; pp. 1 - 4 |
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| Autores principales: | , , , , |
| Formato: | case study pictorial Journal Article |
| Publicado: |
Sage Publications Inc.
6/27/2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=157687641&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 157687641 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2632010X M8A9 jtl: Clinical Pathology issn: 2632010X maglogo: Y pubinfo: dt: 6/27/2022 vid: 15 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 157687641 157687641 157687641 10.1177/2632010X221105224 157687641 ppf: 1 ppct: 3 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Morphological and Ancillary Features of Uterine Leiomyosarcoma: Case Report. aug: au: Boșoteanu, Mădălina Vodă, Raluca Ioana Așchie, Mariana Bosoteanu, Luana-Andreea Bălțătescu, Gabriela Izabela affil: Clinical Service of Pathology, "Sf. Apostol Andrei" Emergency County Hospital, Constanţa, Romania sug: subj: Leiomyosarcoma Physiopathology Uterine Neoplasms Physiopathology Uterus Anatomy and Histology Disease Attributes Middle Age Female Microscopy Uterus Pathology Cell Proliferation Immunohistochemistry Body Fluids Middle Aged: 45-64 years Female ab: We report a rare case of giant uterine leiomyosarcoma in a postmenopausal woman, whose diagnosis was initially suspected at the evaluation of the abdominal efusion, and confirmed after the pathological examination of the uterus in association with the ancillary tests. The evaluation of the abdominal fluid showed single or clusters of malignant, round or spindle-shaped cells. On microscopic examination of the surgical specimen, a dense cell proliferation of spindle cells, with moderate to severe nuclear pleomorphism and significant mitotic activity was observed. Immunohistochemical evaluation demonstrated the loss of myocytic differentiation by focal, weakly positive expression of smooth muscle actin and desmin. The data presented in this case emphasize the relevance of the cytological examination, although the latter has only indicative value, especially since it is an aggressive tumor, frequently associated with mutant expression of p53. In our case, the first indication of the presence of uterine sarcoma was given by the presence of atypical cells in the peritoneal fluid. pubtype: Academic Journal doctype: case study pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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