Artificial Intelligence System for Predicting Prostate Cancer Lesions from Shear Wave Elastography Measurements.
(1) Objective: To design an artificial intelligence system for prostate cancer prediction using the data obtained by shear wave elastography of the prostate, by comparing it with the histopathological exam of the prostate biopsy specimens. (2) Material and methods: We have conducted a prospective st...
| Published in: | Current Oncology Vol. 29; no. 6; pp. 4212 - 4224 |
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| Main Authors: | , , , , , , , |
| Format: | Journal Article |
| Published: |
MDPI
Jun2022
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=157715893&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 157715893 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11980052 5EKK jtl: Current Oncology issn: 11980052 maglogo: N pubinfo: dt: Jun2022 vid: 29 iid: 6 pid: 97109 pub: MDPI artinfo: ui: 157715893 10.3390/curroncol29060336 157715893 ppf: 4212 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Artificial Intelligence System for Predicting Prostate Cancer Lesions from Shear Wave Elastography Measurements. aug: au: Secasan, Ciprian Cosmin Onchis, Darian Bardan, Razvan Cumpanas, Alin Novacescu, Dorin Botoca, Corina Dema, Alis Sporea, Ioan affil: Department of Urology, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania sug: ab: (1) Objective: To design an artificial intelligence system for prostate cancer prediction using the data obtained by shear wave elastography of the prostate, by comparing it with the histopathological exam of the prostate biopsy specimens. (2) Material and methods: We have conducted a prospective study on 356 patients undergoing transrectal ultrasound-guided prostate biopsy, for suspicion of prostate cancer. All patients were examined using bi-dimensional shear wave ultrasonography, which was followed by standard systematic transrectal prostate biopsy. The mean elasticity of each of the twelve systematic biopsy target zones was recorded and compared with the pathological examination results in all patients. The final dataset has included data from 223 patients with confirmed prostate cancer. Three machine learning classification algorithms (logistic regression, a decision tree classifier and a dense neural network) were implemented and their performance in predicting the positive lesions from the elastographic data measurements was assessed. (3) Results: The area under the curve (AUC) results were as follows: for logistic regression—0.88, for decision tree classifier—0.78 and for the dense neural network—0.94. Further use of an upsampling strategy for the training set of the neural network slightly improved its performance. Using an ensemble learning model, which combined the three machine learning models, we have obtained a final accuracy of 98%. (4) Conclusions: Bi-dimensional shear wave elastography could be very useful in predicting prostate cancer lesions, especially when it benefits from the computational power of artificial intelligence and machine learning algorithms. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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