Novel Prehospital Phenotypes and Outcomes in Adult-Patients with Acute Disease.

An early identification of prehospital phenotypes may allow health care workers to speed up and improve patients' treatment. To determine emergency phenotypes by exclusively using prehospital clinical data, a multicenter, prospective, and observational ambulance-based study was conducted with a coho...

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Detalles Bibliográficos
Publicado en:Journal of Medical Systems Vol. 46; no. 7; pp. 1 - 11
Autores principales: Martín-Rodríguez, Francisco, López-Izquierdo, Raúl, Sanz-García, Ancor, del Pozo Vegas, Carlos, Ángel Castro Villamor, Miguel, Mayo-Iscar, Agustín, Martín-Conty, José L., Ortega, Guillermo José
Formato: research tables/charts Journal Article
Publicado: Springer Nature Jul2022
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:An early identification of prehospital phenotypes may allow health care workers to speed up and improve patients' treatment. To determine emergency phenotypes by exclusively using prehospital clinical data, a multicenter, prospective, and observational ambulance-based study was conducted with a cohort of 3,853 adult patients treated consecutively and transferred with high priority from the scene to the hospital emergency department. Cluster analysis determined three clusters with highly different outcome scores and pathological characteristics. The first cluster presented a 30-day mortality after the index event of 45.9%. The second cluster presented a mortality of 26.3%, while mortality of the third cluster was 5.1%. This study supports the detection of three phenotypes with different risk stages and with different clinical, therapeutic, and prognostic considerations. This evidence could allow adapting treatment to each phenotype thereby helping in the decision-making process.