Comparison of cardiac volumetry using real-time MRI during free-breathing with standard cine MRI during breath-hold in children.
Background: Cardiac real-time magnetic resonance imaging (RT-MRI) provides high-quality images even during free-breathing. Difficulties in post-processing impede its use in clinical routine.Objective: To demonstrate the feasibility of quantitative analysis of cardiac free-breathing RT-MRI and to com...
| Published in: | Pediatric Radiology Vol. 52; no. 8; pp. 1462 - 1476 |
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| Main Authors: | , , , , , , , , , , |
| Format: | Journal Article |
| Published: |
Springer Nature
Jul2022
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=157889465&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 157889465 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03010449 O03 jtl: Pediatric Radiology issn: 03010449 maglogo: N pubinfo: dt: Jul2022 vid: 52 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 157889465 157889465 NLM35353211 10.1007/s00247-022-05327-5 NLM35353211 157889465 ppf: 1462 ppct: 14 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Comparison of cardiac volumetry using real-time MRI during free-breathing with standard cine MRI during breath-hold in children. aug: au: Röwer, Lena Maria Radke, Karl Ludger Hußmann, Janina Malik, Halima Uelwer, Tobias Voit, Dirk Frahm, Jens Wittsack, Hans-Joerg Harmeling, Stefan Pillekamp, Frank Klee, Dirk affil: Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Children's Hospital, Moorenstr. 5, 40225, Dusseldorf, Germany sug: subj: Breath Holding Magnetic Resonance Imaging Methods Child Reproducibility of Results Stroke Volume Image Interpretation, Computer Assisted Methods Retrospective Design Short Portable Mental Status Questionnaire Clinical Assessment Tools Scales Ferrans and Powers Quality of Life Index Child: 6-12 years ab: Background: Cardiac real-time magnetic resonance imaging (RT-MRI) provides high-quality images even during free-breathing. Difficulties in post-processing impede its use in clinical routine.Objective: To demonstrate the feasibility of quantitative analysis of cardiac free-breathing RT-MRI and to compare image quality and volumetry during free-breathing RT-MRI in pediatric patients to standard breath-hold cine MRI.Materials and Methods: Pediatric patients (n = 22) received cardiac RT-MRI volumetry during free breathing (1.5 T; short axis; 30 frames per s) in addition to standard breath-hold cine imaging in end-expiration. Real-time images were binned retrospectively based on electrocardiography and respiratory bellows. Image quality and volumetry were compared using the European Cardiovascular Magnetic Resonance registry score, structure visibility rating, linear regression and Bland-Altman analyses.Results: Additional time for binning of real-time images was 2 min. For both techniques, image quality was rated good to excellent. RT-MRI was significantly more robust against artifacts (P < 0.01). Linear regression revealed good correlations for the ventricular volumes. Bland-Altman plots showed a good limit of agreement (LoA) for end-diastolic volume (left ventricle [LV]: LoA -0.1 ± 2.7 ml/m2, right ventricle [RV]: LoA -1.9 ± 3.4 ml/m2), end-systolic volume (LV: LoA 0.4 ± 1.9 ml/m2, RV: LoA 0.6 ± 2.0 ml/m2), stroke volume (LV: LoA -0.5 ± 2.3 ml/m2, RV: LoA -2.6 ± 3.3 ml/m2) and ejection fraction (LV: LoA -0.5 ± 1.6%, RV: LoA -2.1 ± 2.8%).Conclusion: Compared to standard cine MRI with breath hold, RT-MRI during free breathing with retrospective respiratory binning offers good image quality, reduced image artifacts enabling fast quantitative evaluations of ventricular volumes in clinical practice under physiological conditions. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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