Household Transmission of SARS-CoV-2 in Bhutan.

Introduction. The transmission trend of SARS-CoV-2 is continuously evolving. Understanding the dynamics in different settings is crucial for any effective containment measures. We aimed to study the characteristics of household transmission of SARS-CoV-2 in Bhutanese households by determining the tr...

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Publicado en:BioMed Research International pp. 1 - 11
Autores principales: Jatsho, Jimba, Pelzom, Dorji, Dorji, Sithar, Pelzang, Thinley
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 7/8/2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 7/8/2022
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        157896037
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        10.1155/2022/5644454
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        atl: Household Transmission of SARS-CoV-2 in Bhutan.
      aug:
        au:
          Jatsho, Jimba
          Pelzom, Dorji
          Dorji, Sithar
          Pelzang, Thinley
        affil: Department of Pediatrics, Phuentsholing Hospital, Chukha, Bhutan
      sug:
        subj:
          COVID-19 Transmission
          Disease Transmission Risk Factors
          Home Environment
          Human
          Retrospective Design
          Nonexperimental Studies
          Bhutan
          COVID-19 Symptoms
          COVID-19 Epidemiology
          Demography
          Descriptive Statistics
          Confidence Intervals
          Prevalence
      ab: Introduction. The transmission trend of SARS-CoV-2 is continuously evolving. Understanding the dynamics in different settings is crucial for any effective containment measures. We aimed to study the characteristics of household transmission of SARS-CoV-2 in Bhutanese households by determining the transmissibility within household contacts of confirmed COVID-19 index cases and their factors of infectivity. Methods. We conducted a retrospective observational study on household transmission in 306 household contacts of 93 COVID-19 positive index cases diagnosed from April 16, 2021, to June 30, 2021. A pro forma was used to collect data on the epidemiological, demographic, and clinical profile of all recruited individuals. Secondary attack rates (SAR) were calculated, and risk factors for transmission were estimated. Results. 180 of 306 household contacts developed secondary household transmission (SAR 58.8%; 95% CI: 53.2-64.2). The median age of household contacts was 22 years. The median household size was 4 (mean 4.3 ± 2.199) members. Contacts exposed to adult index cases (aPR 1; 95% CI 1, 1.02, p = 0.01) and vaccinated index cases (uPR 0.41, 95% CI 0.25, 0.66, p < 0.001) had a higher SAR and prevalence of secondary infections. Conclusions. Our findings suggest substantial evidence of secondary infections among household contacts, especially in the context of public health mandated lockdowns. Aggressive early contact tracing and case identification with subsequent case isolation from other household members remains a crucial step in preventing secondary transmission.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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