The effect of Bacillus coagulans Unique IS-2 supplementation on plasma amino acid levels and muscle strength in resistance trained males consuming whey protein: a double-blind, placebo-controlled study.
Purpose: The aim of the present study was to assess the effect of Bacillus coagulans Unique IS-2 supplementation on absorption and utilization of protein in resistance-trained males. Methods: In this double blind, placebo-control trial, resistance-trained males (21.08 ± 2.84 years) were randomized t...
| Publicado en: | European Journal of Nutrition Vol. 61; no. 5; pp. 2673 - 2686 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Springer Nature
Aug2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=157956243&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 157956243 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Aug2022 vid: 61 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 157956243 155583122 157956243 157956243 10.1007/s00394-022-02844-9 157956243 ppf: 2673 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The effect of Bacillus coagulans Unique IS-2 supplementation on plasma amino acid levels and muscle strength in resistance trained males consuming whey protein: a double-blind, placebo-controlled study. aug: au: Tarik, Mohamad Ramakrishnan, Lakshmy Bhatia, Nidhi Goswami, Ravindra Kandasamy, Devasenathipathy Roy, Atanu Chandran, Dinu S. Singh, Archna Upadhyay, Ashish Datt Kalaivani, Mani Neelamraju, Jayanthi Madempudi, Ratna Sudha Rajan, Reena affil: Department of Cardiac Biochemistry, All India Institute of Medical Sciences, 110029, New Delhi, India sug: subj: Dietary Supplementation Probiotics Whey Proteins Therapeutic Use Intestinal Absorption Muscle Strength Amino Acids Blood Athletes, Male Resistance Training Treatment Outcomes Human Double-Blind Studies Randomized Controlled Trials Random Assignment Plasma Male Young Adult Whey Proteins Administration and Dosage Bacillus Lactose Blood Prospective Studies Leucine Blood Valine Blood Amino Acids, Branched-Chain Blood Isoleucine Blood Athletic Performance Pretest-Posttest Design Oxygen Consumption Muscle Hypertrophy (Physiology) Body Composition Blood Specimen Collection Serum Creatine Kinase Blood Calcium Blood Iron Blood Biological Markers Blood Inflammation Interleukins Blood Interferons Blood Tumor Necrosis Factor Blood C-Reactive Protein Blood Antioxidants Urinalysis Saliva Enzyme-Linked Immunosorbent Assay Two-Way Analysis of Variance Friedman Test Fisher's Exact Test Wilcoxon Rank Sum Test Unpaired T-Tests Data Analysis Software Descriptive Statistics Repeated Measures Amino Acids Analysis Confidence Intervals Urea Urine Questionnaires Scales Respiratory Tract Infections Signs and Symptoms, Digestive Male ab: Purpose: The aim of the present study was to assess the effect of Bacillus coagulans Unique IS-2 supplementation on absorption and utilization of protein in resistance-trained males. Methods: In this double blind, placebo-control trial, resistance-trained males (21.08 ± 2.84 years) were randomized to consume, either 20 g of whey protein powder {80% whey protein concentrate (WPC80), amounting to 15.4 g protein} with 2 billion CFU Bacillus coagulans Unique IS-2 (supplemental group) or 20 g of whey protein powder and lactose instead of Bacillus coagulans (placebo group) once daily for 60 days with a controlled resistance exercise protocol. The whey protein concentrate (WPC-80) given to both groups had a lactose content of 6.8%. Plasma-free amino acids (PFAAs) were determined at baseline, at 30 and 60 days of supplementation. Muscle strength, hypertrophy, VO2 max, and body composition, and other biochemical parameters were assessed at baseline and end line. Results: A positive effect of probiotic Bacillus coagulans Unique IS-2 supplementation was observed on protein absorption as evidenced by an increase in total PFAA by + 16.1% (p = 0.004). Branched chain amino acids (BCAA) comprising isoleucine (p = 0.016), leucine (p = 0.001), and valine (p = 0.002) were increased by + 33.1% in ITT analysis as compared to placebo after 60 days. At 30 days an increase in isoleucine by + 35% (p = 0.113), leucine by + 43% (p = 0.032), and valine by + 32% (p = 0.017) was observed in ITT analysis. Probiotic effect was shown on exercise performance as evidenced by an increase in one RM of leg press and vertical jump power by + 16.61% (p = 0.024) and + 7.86% (p = 0.007), respectively. Conclusion: Significantly increased absorption of BCAA with supplementation of B. coagulans Unique IS-2 along with whey protein and improvement in leg press and vertical jump power was noted indicating the positive effect of the probiotic on muscle power in the lower body. Trial registration number: CTRI/2017/03/008117; Date:16.03.2017. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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