Integrated Multilayer Omics Reveals the Genomic, Proteomic, and Metabolic Influences of Histidyl Dipeptides on the Heart.

Background Histidyl dipeptides such as carnosine are present in a micromolar to millimolar range in mammalian hearts. These dipeptides facilitate glycolysis by proton buffering. They form conjugates with reactive aldehydes, such as acrolein, and attenuate myocardial ischemia-reperfusion injury. Alth...

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Publicado en:	Journal of the American Heart Association Vol. 11; no. 13; pp. 1 - 21
Autores principales:	Keqiang Yan, Zhanlong Mei, Jingjing Zhao, Islam Prodhan, Md Aminul, Detlef Obal, Katragadda, Kartik, Doelling, Benjamin, Hoetker, David, Posa, Dheeraj Kumar, Liqing He, Xinmin Yin, Shah, Jasmit, Jianmin Pan, Rai, Shesh, Lorkiewicz, Pawel Konrad, Xiang Zhang, Siqi Liu, Bhatnagar, Aruni, Baba, Shahid P., Yan, Keqiang
Formato:	research Journal Article
Publicado:	Wiley-Blackwell 7/5/2022
Acceso en línea:	Ver este registro en EBSCOhost