Reappraisal-related downregulation of amygdala BOLD activation occurs only during the late trial window.
During cognitive reappraisal, an individual reinterprets the meaning of an emotional stimulus to regulate the intensity of their emotional response. Prefrontal cortex activity has been found to support reappraisal and is putatively thought to downregulate the amygdala response to these stimuli. The...
| Published in: | Cognitive, Affective & Behavioral Neuroscience Vol. 22; no. 4; pp. 777 - 788 |
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| Main Authors: | , , , |
| Format: | Journal Article |
| Published: |
Springer Nature
Aug2022
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=158036738&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 158036738 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15307026 NA4 jtl: Cognitive, Affective & Behavioral Neuroscience issn: 15307026 maglogo: N pubinfo: dt: Aug2022 vid: 22 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 158036738 154524909 10.3758/s13415-021-00980-z 158036738 ppf: 777 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Reappraisal-related downregulation of amygdala BOLD activation occurs only during the late trial window. aug: au: Pierce, Jordan E. Blair, R. James R. Clark, Kayla R. Neta, Maital affil: Cognitive and Affective Neuroscience Laboratory, Center for Brain, Biology, and Behavior, University of Nebraska-Lincoln, Lincoln, NE, USA sug: ab: During cognitive reappraisal, an individual reinterprets the meaning of an emotional stimulus to regulate the intensity of their emotional response. Prefrontal cortex activity has been found to support reappraisal and is putatively thought to downregulate the amygdala response to these stimuli. The timing of these regulation-related responses during the course of a trial, however, remains poorly understood. In the current fMRI study, participants were instructed to view or reappraise negative images and then rate how negative they felt following each image. The hemodynamic response function was estimated in 11 regions of interest for the entire time course of the trial including image viewing and rating. Notably, within the amygdala there was no evidence of downregulation in the early (picture viewing) window of the trial, only in the late (rating) window, which also correlated with a behavioral measure of reappraisal success. With respect to the prefrontal regions, some (e.g., inferior frontal gyrus) showed reappraisal-related activation in the early window, whereas others (e.g., middle frontal gyrus) showed increased activation primarily in the late window. These results highlight the temporal dynamics of different brain regions during emotion regulation and suggest that the amygdala response to negative images need not be immediately dampened to achieve successful cognitive reappraisal. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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