Cyclic GAN Model to Classify Breast Cancer Data for Pathological Healthcare Task.

An algorithm framework based on CycleGAN and an upgraded dual-path network (DPN) is suggested to address the difficulties of uneven staining in pathological pictures and difficulty of discriminating benign from malignant cells. CycleGAN is used for color normalization in pathological pictures to tac...

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Publicado en:BioMed Research International pp. 1 - 13
Autores principales: Chopra, Pooja, Junath, N., Singh, Sitesh Kumar, Khan, Shakir, Sugumar, R., Bhowmick, Mithun
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 7/21/2022
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: BioMed Research International
      issn: 23146133
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    pubinfo:
      dt: 7/21/2022
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        158121110
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        10.1155/2022/6336700
        158121110
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      tig:
        atl: Cyclic GAN Model to Classify Breast Cancer Data for Pathological Healthcare Task.
      aug:
        au:
          Chopra, Pooja
          Junath, N.
          Singh, Sitesh Kumar
          Khan, Shakir
          Sugumar, R.
          Bhowmick, Mithun
        affil: School of Computer Applications, Lovely Professional University, Phagwara, Punjab, India
      sug:
        subj:
          Breast Neoplasms Diagnosis
          Algorithms
          Staining and Labeling Methods
          Neural Networks (Computer)
          Deep Learning
          False Positive Results
          False Negative Results
          Cell Line, Tumor
      ab: An algorithm framework based on CycleGAN and an upgraded dual-path network (DPN) is suggested to address the difficulties of uneven staining in pathological pictures and difficulty of discriminating benign from malignant cells. CycleGAN is used for color normalization in pathological pictures to tackle the problem of uneven staining. However, the resultant detection model is ineffective. By overlapping the images, the DPN uses the addition of small convolution, deconvolution, and attention mechanisms to enhance the model's ability to classify the texture features of pathological images on the BreaKHis dataset. The parameters that are taken into consideration for measuring the accuracy of the proposed model are false-positive rate, false-negative rate, recall, precision, and F 1 score. Several experiments are carried out over the selected parameters, such as making comparisons between benign and malignant classification accuracy under different normalization methods, comparison of accuracy of image level and patient level using different CNN models, correlating the correctness of DPN68-A network with different deep learning models and other classification algorithms at all magnifications. The results thus obtained have proved that the proposed model DPN68-A network can effectively classify the benign and malignant breast cancer pathological images at various magnifications. The proposed model also is able to better assist the pathologists in diagnosing the patients by synthesizing the images of different magnifications in the clinical stage.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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