Current and New Novel Combination Treatments for Metastatic Triple-Negative Breast Cancer.
Triple-negative breast cancer (TNBC) has a worse prognosis and remains the most challenging breast cancer subtype to treat. This is largely related to the heterogeneity of this disease and the lack of reliable oncological targets. In this review, we discuss the current standard-of-care treatment opt...
| Publicado en: | Current Oncology Vol. 29; no. 7; pp. 4748 - 4768 |
|---|---|
| Autores principales: | , , |
| Formato: | Journal Article |
| Publicado: |
MDPI
Jul2022
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=158209850&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 158209850 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11980052 5EKK jtl: Current Oncology issn: 11980052 maglogo: N pubinfo: dt: Jul2022 vid: 29 iid: 7 pid: 97109 pub: MDPI artinfo: ui: 158209850 10.3390/curroncol29070377 158209850 ppf: 4748 ppct: 20 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Current and New Novel Combination Treatments for Metastatic Triple-Negative Breast Cancer. aug: au: Pauls, Mehrnoosh Chia, Stephen LeVasseur, Nathalie affil: BC Cancer Vancouver Centre, University of British Columbia, 600 W 10th Ave, Vancouver, BC V5Z 4E6, Canada sug: ab: Triple-negative breast cancer (TNBC) has a worse prognosis and remains the most challenging breast cancer subtype to treat. This is largely related to the heterogeneity of this disease and the lack of reliable oncological targets. In this review, we discuss the current standard-of-care treatment options for metastatic TNBC, including recent advances with the use of immunotherapy, PARP inhibitors and antibody-drug conjugates. This review also explores new agents and novel combinations arising in the field for the treatment of advanced TNBC. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|