Diagnostic Significance of 3D Automated Breast Volume Scanner in a Combination with Contrast-Enhanced Ultrasound for Breast Cancer.

The incidence of cancer is increasing today, particularly lung and chest cancer. Employing novel methods to detect cancer in its earliest stages and discover painless, noninvasive treatments are urgently needed. The goal of the proposed study is to investigate the value of automated breast volume sc...

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Published in:BioMed Research International pp. 1 - 9
Main Authors: Yuan, Quan, Song, Canxu, Tian, Yan, Chen, Nan, He, Xing, Wang, Ying, Han, Pihua
Format: research tables/charts Journal Article
Published: Wiley-Blackwell 8/3/2022
Online Access:View this record in EBSCOhost
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      dt: 8/3/2022
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2022/3199884
        158330796
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        atl: Diagnostic Significance of 3D Automated Breast Volume Scanner in a Combination with Contrast-Enhanced Ultrasound for Breast Cancer.
      aug:
        au:
          Yuan, Quan
          Song, Canxu
          Tian, Yan
          Chen, Nan
          He, Xing
          Wang, Ying
          Han, Pihua
        affil: Department of Ultrasound, Shaanxi Provincial Cancer Hospital, Xi'an 710061, China
      sug:
        subj:
          Early Detection of Cancer
          Breast Neoplasms Ultrasonography
          Diagnostic Imaging
          Neoadjuvant Therapy
          Chemotherapy, Cancer
          China
          Human
          Female
          ROC Curve
          Multiple Linear Regression
          Descriptive Statistics
          Data Analysis Software
          T-Tests
          Analysis of Variance
          Chi Square Test
          Female
      ab: The incidence of cancer is increasing today, particularly lung and chest cancer. Employing novel methods to detect cancer in its earliest stages and discover painless, noninvasive treatments are urgently needed. The goal of the proposed study is to investigate the value of automated breast volume scanning (ABUS) in conjunction with contrast-enhanced ultrasonography (CEUS) in properly diagnosing breast cancer in its early stages and the effectiveness of neoadjuvant chemotherapy (NAC) in treating the disease. For the research study, information on 98 patients who had NAC and surgery in the breast surgery department of the Shaanxi Provincial Cancer Hospital has been gathered. All patients have received four cycles of NAC and underwent conventional ultrasound (HUSS), CEUS, ABUS, and pathological examination. At the same time, receiver operating characteristic (ROC) curve analysis, single factor, multiple linear regression, and other methods have also been used to analyze the diagnostic efficacy of breast cancer and NAC efficacy evaluation results. The study of this paper is totally based on the data collected from Shaanxi Provincial Cancer Hospital. The statistical and computational analyses are performed on the data collected for drawing inferences. When the findings are compared to the results of the pathological examination, HUSS has demonstrated a significant distinction between benign and malignant diagnoses with a statistical value of P < 0.05.ABUS combined with CEUS has shown no considerable differences in correlation study. Except for negative likelihood ratio, the diagnostic performance indexes of CEUS+ ABUS are substantially higher than HHUS with P < 0.05. ROC curve analysis is also performed which shows that CEUS and ABUS combination has higher precision in the analysis of breast cancer. ABUS pooled with CEUS shows great application value in the judgment of breast cancer as per the results obtained from the statistical analysis on data of 98 patients.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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