A New Approach to Disease, Risk, and Boundaries Based on Emergent Probability.
The status of risk factors and disease remains a disputed question in the theory and practice of medicine and healthcare, and so does the related question of delineating disease boundaries. I present a framework based on Bernard Lonergan's account of emergent probability for differentiating (1) gene...
| Publicado en: | Journal of Medicine & Philosophy Vol. 47; no. 3; pp. 457 - 482 |
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| Autor principal: | |
| Formato: | Journal Article |
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Oxford University Press / USA
Jun2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=158364694&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 158364694 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03605310 MPS jtl: Journal of Medicine & Philosophy issn: 03605310 maglogo: N pubinfo: dt: Jun2022 vid: 47 iid: 3 pid: 622 pub: Oxford University Press / USA artinfo: ui: 158364694 158364694 NLM35779075 10.1093/jmp/jhac001 NLM35779075 158364694 ppf: 457 ppct: 25 formats: fmt: – @attributes: type: T db: hlh ui: 158364694 – @attributes: type: P db: hlh ui: 158364694 tig: atl: A New Approach to Disease, Risk, and Boundaries Based on Emergent Probability. aug: au: Daly, Patrick affil: Lonergan Institute at Boston College , Boston, Massachusetts , USA sug: subj: Medicine Health Care Delivery Probability Clinical Assessment Tools ab: The status of risk factors and disease remains a disputed question in the theory and practice of medicine and healthcare, and so does the related question of delineating disease boundaries. I present a framework based on Bernard Lonergan's account of emergent probability for differentiating (1) generically distinct levels of systematic function within organisms and between organisms and their environments and (2) the methods of functional, genetic, and statistical investigation. I then argue on this basis that it is possible to understand disease in terms of biological or higher intra-level dysfunction, risk factors-including genetic risk factors-in terms of statistical inter-level conditioning of a given stage or developmental sequence of systematic functioning, and the empirical boundaries of disease in terms of the limits of both functional categorization (from an epistemic standpoint) and upper-level integration of lower-level processes and events (from an ontological standpoint). pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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