Population pharmacokinetic modelling of imatinib in healthy subjects receiving a single dose of 400 mg.

Purpose: Imatinib is indicated for treatment of CML, GIST, etc. The population pharmacokinetics (popPK) of imatinib in patients under long-term treatment are reported in literature. Data obtained from bioequivalence trials for healthy subjects were used to evaluate the influence of demographic and p...

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Publicado en:Cancer Chemotherapy & Pharmacology Vol. 90; no. 2; pp. 125 - 137
Autores principales: Chien, Yi-Han, Würthwein, Gudrun, Zubiaur, Pablo, Posocco, Bianca, Pena, María Ángeles, Borobia, Alberto M., Gagno, Sara, Abad-Santos, Francisco, Hempel, Georg
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Aug2022
Acceso en línea:Ver este registro en EBSCOhost