Patient age affects sex-based differences in post-traumatic mortality: a national trauma registry study in Japan.
Purpose: Sex-based differences in post-traumatic mortality have been widely discussed for quite some time. We hypothesized that age-related pathophysiologic changes would affect sex-based differences in post-traumatic mortality and aimed to verify the hypothesis using a nationwide trauma registry in...
| Publicado en: | European Journal of Trauma & Emergency Surgery Vol. 48; no. 4; pp. 2731 - 2741 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Aug2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=158431649&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 158431649 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18639933 3C05 jtl: European Journal of Trauma & Emergency Surgery issn: 18639933 maglogo: N pubinfo: dt: Aug2022 vid: 48 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 158431649 153923896 158431649 158431649 10.1007/s00068-021-01840-8 158431649 ppf: 2731 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Patient age affects sex-based differences in post-traumatic mortality: a national trauma registry study in Japan. aug: au: Umemura, Yutaka Katayama, Yusuke Kitamura, Tetsuhisa Kiyohara, Kosuke Hirose, Tomoya Kiguchi, Takeyuki Tachino, Jotaro Nakao, Shunichiro Nakagawa, Yuko Shimazu, Takeshi affil: Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, 2‑15 Yamada‑oka, 565-0871, Suita, Osaka, Japan sug: subj: Stress Disorders, Post-Traumatic Mortality Age Factors Sex Factors Japan Human ab: Purpose: Sex-based differences in post-traumatic mortality have been widely discussed for quite some time. We hypothesized that age-related pathophysiologic changes would affect sex-based differences in post-traumatic mortality and aimed to verify the hypothesis using a nationwide trauma registry in Japan. Methods: This was a retrospective analysis of trauma patients registered in The Japanese Trauma Data Bank. We stratified the study population into the following three subsets based on age: (1) pediatric subset (age ≤ 14), (2) adult subset (age 15–50) and (3) senior adult subset (age ≥ 51). We evaluated both sex-based differences in mortality in each subset separately using multivariate logistic regression analysis and the two-way interaction effect for predicted survival between the continuous increase of age and the sexes using a nonlinear multivariate regression model. Results: We included 122,819 trauma patients who fulfilled the inclusion criteria and classified them into the 3 subsets according to age. Male patients were more likely to die compared to female patients only in the senior adult subset (adjusted odds ratio: 1.26; 95% confidence interval: 1.18–1.36), whereas there were no statistically significant differences in the other two subsets. Furthermore, non-linear logistic regression analysis revealed that predicted survival probability in male patients decreased more sharply in accordance with the increase of age compared to that in female patients (p for interaction: 0.051). Conclusion: Age-related change in post-traumatic mortality was significantly different between males and females, and male patients had a relatively higher risk of death in the older population. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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