Is there a combined effect of depression and cognitive reserve on cognitive function? Findings from a population-based study.

To analyse the combined effect of depression and cognitive reserve (CR) on cognition over a three-year follow-up period; and to explore this relationship specifically in individuals aged 65+ years. Data from the 'Edad con Salud' project were analysed (n = 1,144; 50+ years). The Composite Internation...

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Publicado en:Psychology & Health Vol. 37; no. 9; pp. 1132 - 1148
Autores principales: Lara, Elvira, Martín-María, Natalia, Miret, Marta, Olaya, Beatriz, Haro, Josep Maria, Ayuso-Mateos, José Luis
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Sep2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2022
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        10.1080/08870446.2021.1927030
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        atl: Is there a combined effect of depression and cognitive reserve on cognitive function? Findings from a population-based study.
      aug:
        au:
          Lara, Elvira
          Martín-María, Natalia
          Miret, Marta
          Olaya, Beatriz
          Haro, Josep Maria
          Ayuso-Mateos, José Luis
        affil: Department of Psychiatry, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-Princesa), Madrid, Spain
      sug:
        subj:
          Depression Complications
          Cognition Evaluation
          Human
          Aged
          Episodic Memory
          Word Lists
          Speech
          Regression
          Interview Guides
          After Care
          Questionnaires
          Task Performance and Analysis
          Aged: 65+ years
      ab: To analyse the combined effect of depression and cognitive reserve (CR) on cognition over a three-year follow-up period; and to explore this relationship specifically in individuals aged 65+ years. Data from the 'Edad con Salud' project were analysed (n = 1,144; 50+ years). The Composite International Diagnostic Interview was used to evaluate depression. CR was assessed with the Cognitive Reserve Questionnaire. Episodic memory was assessed with the word list memory and recall. Verbal fluency was measured through the animal naming task. Random coefficient regression analyses were performed. Depression was associated with lower scores in episodic memory, whereas increased levels of CR were related with higher scores across all the cognitive tests. Among older-aged individuals, cognition decreased at lower levels of CR regardless of depression, while participants with depression exhibited decreased values in both measures of memory at higher levels of CR. Depression and CR were related with cognitive performance. Among older individuals, those with low levels of CR may constitute a vulnerable group with poor cognitive prognosis, whilst a harmful effect of depression on memory performance was observed among individuals with greater CR. Further evidence needs to be gathered to understand these associations.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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