Meta-Analysis of the Comprehensive Efficacy of Intraocular Lens Implantation in Glaucoma Patients.
This study is aimed at investigating the efficacy of intraocular lens (IOL) implantation in patients suffering from glaucoma through meta-analysis of the previously published research. For this purpose, different literature databases were searched for identification of clinical studies published bet...
| Publicado en: | BioMed Research International pp. 1 - 12 |
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| Autor principal: | |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
8/16/2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=158544204&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 158544204 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 8/16/2022 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 158544204 158544204 158544204 10.1155/2022/5130416 158544204 ppf: 1 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Meta-Analysis of the Comprehensive Efficacy of Intraocular Lens Implantation in Glaucoma Patients. aug: au: Zhou, Qingyi affil: Department of Ophthalmology. Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, 158 Shangtang Road, Hangzhou, 310014 Zhejiang, China sug: subj: Glaucoma Surgery Lenses, Intraocular Treatment Outcomes Evaluation Human Systematic Review Meta Analysis Data Analysis Software Cornea Anatomy and Histology Anterior Chamber Endothelial Cells Visual Acuity Intraocular Pressure Antiglaucoma Agents Postoperative Complications Descriptive Statistics Chi Square Test Confidence Intervals ab: This study is aimed at investigating the efficacy of intraocular lens (IOL) implantation in patients suffering from glaucoma through meta-analysis of the previously published research. For this purpose, different literature databases were searched for identification of clinical studies published between January 2000 and January 2022 on evaluating IOL's efficacy in treating glaucoma. RevMan 5.3 was used to conduct a meta-analysis of the pertinent data. The central anterior chamber depth (ACD), corneal endothelial cell counts, best-corrected visual acuity (BCVA), intraocular pressure (IOP), anti-glaucoma medications (AGM), and axial length (AL) changes were compared, and the incidence of postoperative complications was thoroughly evaluated. The Cochran chi-square test was used to examine the heterogeneity of the evaluation results. According to the inclusion and exclusion criteria, 20 studies included 948 glaucomatous eyes. IOP was significantly lower than before treatment (MD = 8.64 , 95 CI: 5.75-11.53; Z = 5.86 , P < 0.0001), while ACD increased significantly (MD = − 1.38 , 95 percent CI: -1.74-1.02; Z = 7.49 , P < 0.0001). The corneal endothelial cell counts were homogeneous (MD = 225.08 , 95% CI: -64.17 to -514.33; Z = 1.53 , P = 0.20). AGM utilisation decreased (MD = 1.43 , 95% CI: 0.752.12, Z = 4.09 , P < 0.0001). AL decreased significantly (MD = 0.31 ; 95% CI: 0.09-0.54; Z = 2.71 ; P = 0.007). The incidence of complications remained insignificant after IOL treatment (OR = 1.05 , 95% CI: 0.42 to 2.60; Z = 0.10 , P = 0.92 ; P = 0.92). These findings indicate that IOL treatment can significantly reduce intraocular pressure, glaucoma drug use, and aqueous level (AL) in glaucoma patients while increasing the depth of the central anterior chamber. This study offers a theoretical foundation for selecting glaucoma treatment methods. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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