Metabolomic profiling relates tianeptine effectiveness with hippocampal GABA, myo-inositol, cholesterol, and fatty acid metabolism restoration in socially isolated rats.

Rationale: Discovering biomarkers of major depressive disorder (MDD) can give a deeper understanding of this mood disorder and improve the ability to screen for, diagnose, and treat MDD. Objectives: In this study, metabolomics was used in unraveling metabolite fluctuations of MDD and drug outcome by...

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Detalles Bibliográficos
Publicado en:Psychopharmacology Vol. 239; no. 9; pp. 2955 - 2975
Autores principales: Perić, Ivana, Lješević, Marija, Beškoski, Vladimir, Nikolić, Milan, Filipović, Dragana
Formato: Journal Article
Publicado: Springer Nature Sep2022
Acceso en línea:Ver este registro en EBSCOhost