High-Resolution Histopathological Image Classification Model Based on Fused Heterogeneous Networks with Self-Supervised Feature Representation.

Applying machine learning technology to automatic image analysis and auxiliary diagnosis of whole slide image (WSI) may help to improve the efficiency, objectivity, and consistency of pathological diagnosis. Due to its extremely high resolution, it is still a great challenge to directly process WSI...

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Publicado en:BioMed Research International pp. 1 - 11
Autores principales: Lai, Zhi-Fei, Zhang, Gang, Zhang, Xiao-Bo, Liu, Hong-Tao
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 8/21/2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 8/21/2022
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2022/8007713
        158630394
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        atl: High-Resolution Histopathological Image Classification Model Based on Fused Heterogeneous Networks with Self-Supervised Feature Representation.
      aug:
        au:
          Lai, Zhi-Fei
          Zhang, Gang
          Zhang, Xiao-Bo
          Liu, Hong-Tao
        affil: Information Engineering College, Guangzhou Panyu Polytechnic, Guangzhou 511483, China
      sug:
        subj:
          Microscopy
          Image Processing, Computer Assisted
          Neural Networks (Computer)
          Human
          Machine Learning
          Deep Learning
          Automation
          Sensitivity and Specificity
          Diagnosis, Computer Assisted
      ab: Applying machine learning technology to automatic image analysis and auxiliary diagnosis of whole slide image (WSI) may help to improve the efficiency, objectivity, and consistency of pathological diagnosis. Due to its extremely high resolution, it is still a great challenge to directly process WSI through deep neural networks. In this paper, we propose a novel model for the task of classification of WSIs. The model is composed of two parts. The first part is a self-supervised encoding network with a UNet-like architecture. Each patch from a WSI is encoded as a compressed latent representation. These features are placed according to their corresponding patch's original location in WSI, forming a feature cube. The second part is a classification network fused by 4 famous network blocks with heterogeneous architectures, with feature cube as input. Our model effectively expresses the feature and preserves location information of each patch. The fused network integrates heterogeneous features generated by different networks which yields robust classification results. The model is evaluated on two public datasets with comparison to baseline models. The evaluation results show the effectiveness of the proposed model.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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