The effectiveness of laser vitreolysis for vitreous floaters in posterior vitreous detachment.

Purpose: To determine the effectiveness of laser vitreolysis in terms of contrast sensitivity function (CSF) and vision-related quality of life (VRQol) for symptomatic floaters due to posterior vitreous detachment (PVD).Materials: This is an interventional study that involved 57 eyes of 45 patients...

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Published in:Indian Journal of Ophthalmology Vol. 70; no. 8; pp. 3026 - 3033
Main Authors: Goh, Wan, Mustapha, Mushawiahti, Zakaria, Syed, Bastion, Mae-Lynn, Goh, Wan Ni, Zakaria, Syed Z S, Bastion, Mae-Lynn C
Format: pictorial research tables/charts Journal Article
Published: Wolters Kluwer India Pvt Ltd Aug2022
Online Access:View this record in EBSCOhost
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      dt: Aug2022
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      pub: Wolters Kluwer India Pvt Ltd
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        atl: The effectiveness of laser vitreolysis for vitreous floaters in posterior vitreous detachment.
      aug:
        au:
          Goh, Wan
          Mustapha, Mushawiahti
          Zakaria, Syed
          Bastion, Mae-Lynn
          Goh, Wan Ni
          Zakaria, Syed Z S
          Bastion, Mae-Lynn C
        affil: Department of Ophthalmology, Universiti Kebangsaan Malaysia (UKM) Medical Centre, Kuala Lumpur
      sug:
        subj:
          Eye Diseases Diagnosis
          Laser Therapy
          Eye Diseases Surgery
          Lasers Therapeutic Use
          Quality of Life
          Questionnaires
      ab: Purpose: To determine the effectiveness of laser vitreolysis in terms of contrast sensitivity function (CSF) and vision-related quality of life (VRQol) for symptomatic floaters due to posterior vitreous detachment (PVD).Materials: This is an interventional study that involved 57 eyes of 45 patients with symptomatic floaters for more than 3 months. Patients underwent one to three sessions of vitreolysis via Neodymiun-doped Yttrium Aluminum Garnet (Nd:YAG) laser. We examined the CSF using the computer programs Freiburg Acuity and Contrast Test (FrACT) and VRQoL survey using the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25) before, and 1 month after, vitreolysis.Results: Twelve patients had both eyes lasered and 33 patients had one eye lasered. The mean CSF improved from 3.20 ± 0.85%W to 2.64 ± 0.63%W 1 month after vitreolysis. Each use of the laser showed a significant mean difference in CSF (%W) as analyzed by paired t-test before and after the first laser (0.29 ± 0.49%W [P ≤ 0.001]); after the first and second laser (0.35 ± 0.53%W [P = 0.01]); and after second and third laser (0.21 ± 0.31%W [P = 0.02]). There was improvement in the median of four subscales in NEI VFQ-25 scores post treatment: general vision (z = -3.30, P = 0.001), near activity (z = 3.396, P = 0.001, distance activity (z = -2.788, P = 0.005), and mental health (z = -2.219, P = 0.026). The mean scores increased to 79.55 ± 9.45 from the baseline 75.06 ± 9.69 (P ≤ 0.001). No adverse events were recorded 1 month after the laser treatments.Conclusion: Vitreolysis by Nd:YAG laser improved the CFS and VRQoL in symptomatic PVD patients.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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