Pattern and Visual Prognostic Factors of Behcet's Uveitis in Northwest Iran.
Purpose: To investigate the pattern of ocular involvement in Behcet's disease (BD) with predictors of patients' final state of vision. Methods: This historical cohort encompassed the clinical records of 200 patients diagnosed according to the International Criteria for BD (ICBD), over a period of 17...
| Publicado en: | Journal of Ophthalmic & Vision Research Vol. 17; no. 2; pp. 242 - 252 |
|---|---|
| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Knowledge E DMCC
Apr-Jun2022
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=158658896&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 158658896 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20082010 AY5S jtl: Journal of Ophthalmic & Vision Research issn: 20082010 maglogo: N pubinfo: dt: Apr-Jun2022 vid: 17 iid: 2 pid: 35682 pub: Knowledge E DMCC artinfo: ui: 158658896 158658896 158658896 10.18502/jovr.v17i2.10796 158658896 ppf: 242 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Pattern and Visual Prognostic Factors of Behcet's Uveitis in Northwest Iran. aug: au: Ghavidel, Leila Alizadeh Bagheri, Masood Mousavi, Farideh Rezaei, Leila Hazeri, Somayyeh Hashemi, Hesam-Sadat affil: Cornea & External Eye Diseases, Department of Ophthalmology, Royal Victoria hospital, McGill University, Montreal, Canada sug: subj: Behcet's Syndrome Epidemiology Behcet's Syndrome Prognosis Uveitis, Anterior Prognosis Human Iran Nonconcurrent Prospective Studies Prevalence Male Female Macular Edema Univariate Statistics Multivariate Analysis Record Review Visual Acuity Data Analysis Software Descriptive Statistics Analysis of Variance Chi Square Test Cox Proportional Hazards Model Behcet's Syndrome Risk Factors Uveitis, Anterior Risk Factors Adult Middle Age Behcet's Syndrome Drug Therapy Treatment Outcomes Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Purpose: To investigate the pattern of ocular involvement in Behcet's disease (BD) with predictors of patients' final state of vision. Methods: This historical cohort encompassed the clinical records of 200 patients diagnosed according to the International Criteria for BD (ICBD), over a period of 17 years between 2004 and 2021. Results: The prevalence of Behcet's uveitis (BU) was more common in females and patients in the fourth decade of life. Ninety-five patients (47.5%) had evidence of ocular involvement in the initial ophthalmologic evaluation, and 171 patients (85.5%) manifested evidence of BU during the follow-up visits of which bilateral non-granulomatous panuveitis was the most common anatomical pattern of involvement (32.9%) followed by posterior (27.6%), anterior (26.5%), and intermediate (13.8%) uveitis. The prevalent accompanying signs were oral aphthous (67%), skin lesions (29%), and genital ulcers (19.5%). Cystoid macular edema (CME) was the most frequent ocular complication (62%), followed by cataract (57.5%) and epiretinal membranes (ERM) (36.5%). Univariate analysis showed the following determinants: male gender, younger age at onset, panuveitis, posterior uveitis, retinal vasculitis, and longer duration of uveitis as poorer visual prognostic factors of the disease. Multivariate analysis demonstrated a higher chance of poor visual prognosis of BD in patients with panuveitis, posterior uveitis, retinal vasculitis, and longer duration of uveitis. Conclusion: This cohort study demonstrated an overview on epidemiological patterns of BU along with the visual prognostic factors in Iranian patients. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|