Quality of life in pediatric patients with obsessive–compulsive disorder during and 3 years after stepped-care treatment.
The present study aimed to investigate the long-term quality of life (QoL) in a large sample of pediatric obsessive–compulsive disorder (OCD) patients. The study included 220 pediatric OCD patients from the Nordic Long-term OCD Treatment Study (NordLOTS) who were evaluated at seven time points befor...
| Publicado en: | European Child & Adolescent Psychiatry Vol. 31; no. 9; pp. 1377 - 1390 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Sep2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=158694109&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 158694109 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10188827 EJ3 jtl: European Child & Adolescent Psychiatry issn: 10188827 maglogo: N pubinfo: dt: Sep2022 vid: 31 iid: 9 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 158694109 149916461 158694109 158694109 10.1007/s00787-021-01775-w 158694109 ppf: 1377 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Quality of life in pediatric patients with obsessive–compulsive disorder during and 3 years after stepped-care treatment. aug: au: Jensen, Sanne Hybel, Katja A. Højgaard, Davíð R. M. A. Nissen, Judith Becker Weidle, Bernhard Ivarsson, Tord Skarphedinsson, Gudmundur Melin, Karin Torp, Nor Christian Carlsen, Anders Helles Mortensen, Erik Lykke Lenhard, Fabian Compton, Scott Thomsen, Per Hove affil: Department of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry, Denmark sug: subj: Obsessive-Compulsive Disorder Therapy Health Care Delivery Methods Quality of Life Evaluation Treatment Outcomes Human Female Male Child Adolescence Questionnaires Pretest-Posttest Design Multivariate Analysis Behavioral Symptoms Comorbidity Child: 6-12 years Adolescent: 13-18 years Female Male ab: The present study aimed to investigate the long-term quality of life (QoL) in a large sample of pediatric obsessive–compulsive disorder (OCD) patients. The study included 220 pediatric OCD patients from the Nordic Long-term OCD Treatment Study (NordLOTS) who were evaluated at seven time points before, during, and after stepped-care treatment over a 3-year follow-up period. Data from three symptom severity trajectory classes formed the basis of the QoL evaluation: acute (n = 127, N = 147), slow (n = 46, N = 63), and limited responders (n = 47, N = 59). Patients' QoL was assessed using parent and child ratings of the revised Questionnaire for Measuring Health-related Quality of Life in Children and Adolescents (KINDL-R). QoL was analyzed by trajectory class using a random mixed effects model. The association between pre-treatment factors and long-term QoL was investigated across classes in a multivariate model. Three years after treatment, the acute responder class had reached QoL levels from a general population, whereas the limited responder class had not. The slow responder class reached norm levels for the child-rated QoL only. Higher levels of co-occurring externalizing symptoms before treatment were associated with lower parent-rated QoL during follow-up, while adolescence and higher levels of co-occurring internalizing symptoms were associated with lower child-rated QoL during follow-up. For some patients, residual OCD symptoms in the years after treatment, even at levels below assumed clinical significance, are associated with compromised QoL. Co-occurring symptoms could be part of the explanation. Assessing QoL after OCD treatment, beyond the clinician-rated symptom severity, could detect patients in need of further treatment and/or assessment. Trial registry: Nordic Long-term Obsessive–Compulsive Disorder (OCD) Treatment Study; www.controlled-trials.com; ISRCTN66385119. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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