Possible Bias in Supervised Deep Learning Algorithms for CT Lung Nodule Detection and Classification.

Simple Summary: Artificial Intelligence (AI) algorithms can assist clinicians in their daily tasks by automatically detecting and/or classifying nodules in chest CT scans. Bias of such algorithms is one of the reasons why implementation of them in clinical practice is still not widely adopted. There...

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Published in:Cancers Vol. 14; no. 16; pp. 3867 - 3882
Main Authors: Sourlos, Nikos, Wang, Jingxuan, Nagaraj, Yeshaswini, van Ooijen, Peter, Vliegenthart, Rozemarijn
Format: diagnostic images review tables/charts Journal Article
Published: MDPI Aug2022
Online Access:View this record in EBSCOhost
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      dt: Aug2022
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      pub: MDPI
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        10.3390/cancers14163867
        158750435
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      formats:
      tig:
        atl: Possible Bias in Supervised Deep Learning Algorithms for CT Lung Nodule Detection and Classification.
      aug:
        au:
          Sourlos, Nikos
          Wang, Jingxuan
          Nagaraj, Yeshaswini
          van Ooijen, Peter
          Vliegenthart, Rozemarijn
        affil: Department of Radiology, University Medical Center of Groningen, 9713 GZ Groningen, The Netherlands
      sug:
        subj:
          Solitary Pulmonary Nodule Diagnosis
          Solitary Pulmonary Nodule Classification
          Solitary Pulmonary Nodule Radiography
          Tomography, X-Ray Computed
          Deep Learning Methods
          Artificial Intelligence Utilization
          Algorithms Utilization
          Bias (Research)
          Early Detection of Cancer
      ab: Simple Summary: Artificial Intelligence (AI) algorithms can assist clinicians in their daily tasks by automatically detecting and/or classifying nodules in chest CT scans. Bias of such algorithms is one of the reasons why implementation of them in clinical practice is still not widely adopted. There is no published review on the bias that these algorithms may contain. This review aims to present different types of bias in such algorithms and present possible ways to mitigate them. Only then it would be possible to ensure that these algorithms work as intended under many different clinical settings. Artificial Intelligence (AI) algorithms for automatic lung nodule detection and classification can assist radiologists in their daily routine of chest CT evaluation. Even though many AI algorithms for these tasks have already been developed, their implementation in the clinical workflow is still largely lacking. Apart from the significant number of false-positive findings, one of the reasons for that is the bias that these algorithms may contain. In this review, different types of biases that may exist in chest CT AI nodule detection and classification algorithms are listed and discussed. Examples from the literature in which each type of bias occurs are presented, along with ways to mitigate these biases. Different types of biases can occur in chest CT AI algorithms for lung nodule detection and classification. Mitigation of them can be very difficult, if not impossible to achieve completely.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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