Reliability of Addenbrooke's Cognitive Examination III in differentiating between dementia, mild cognitive impairment and older adults who have not reported cognitive problems.
Diagnosing dementia can be challenging for clinicians, given the array of factors that contribute to changes in cognitive function. The Addenbrooke's Cognitive Examination III (ACE-III) is commonly used in dementia assessments, covering the domains of attention, memory, fluency, visuospatial and lan...
| Publicado en: | European Journal of Ageing Vol. 19; no. 3; pp. 495 - 508 |
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| Autores principales: | , , , , , , , , |
| Formato: | Artículo |
| Publicado: |
Springer Nature
Sep2022
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=158783761&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 158783761 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 16139372 3RAL jtl: European Journal of Ageing issn: 16139372 maglogo: N pubinfo: dt: Sep2022 vid: 19 iid: 3 pid: 237 pub: Springer Nature artinfo: ui: 158783761 10.1007/s10433-021-00652-4 ppf: 495 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P size: 1.5MB tig: atl: Reliability of Addenbrooke's Cognitive Examination III in differentiating between dementia, mild cognitive impairment and older adults who have not reported cognitive problems. aug: au: Potts, C. Richardson, J. Bond, R. B. Price, R. K. Mulvenna, M. D. Zvolsky, P. Harvey, M. Hughes, C. F. Duffy, F. affil: Faculty of Computing, School of Computing, Engineering and the Built Environment, Ulster University, Newtownabbey, Coleraine, UK Memory Service, Northern Health and Social Care Trust, Antrim, UK Faculty of Life and Health Sciences, School of Biomedical Sciences, Ulster University, Coleraine, UK su: Memory Language acquisition Attention Reading Old age Cognition disorders diagnosis Diagnosis of dementia Alzheimer's disease diagnosis Research evaluation Research methodology evaluation Research methodology Acquisition of data Neuropsychological tests Visual perception Medical records Descriptive statistics sug: subj: Memory Language acquisition Attention Reading Old age Cognition disorders diagnosis Diagnosis of dementia Alzheimer's disease diagnosis Research evaluation Research methodology evaluation Research methodology Acquisition of data Neuropsychological tests Visual perception Medical records Descriptive statistics keyword: Alzheimer's disease Cognitive assessment Cognitive screening test MCI NHSCT Memory Service Vascular dementia Alzheimer's disease Cognitive assessment Cognitive screening test MCI NHSCT Memory Service Vascular dementia ab: Diagnosing dementia can be challenging for clinicians, given the array of factors that contribute to changes in cognitive function. The Addenbrooke's Cognitive Examination III (ACE-III) is commonly used in dementia assessments, covering the domains of attention, memory, fluency, visuospatial and language. This study aims to (1) assess the reliability of ACE-III to differentiate between dementia, mild cognitive impairment (MCI) and controls and (2) establish whether the ACE-III is useful for diagnosing dementia subtypes. Client records from the Northern Health and Social Care Trust (NHSCT) Memory Service (n = 2,331, 2013–2019) were used in the analysis including people diagnosed with Alzheimer's disease (n = 637), vascular dementia (n = 252), mixed dementia (n = 490), MCI (n = 920) and controls (n = 32). There were significant differences in total ACE-III and subdomain scores between people with dementia, MCI and controls (p < 0.05 for all), with little overlap between distribution of total ACE-III scores (< 39%) between groups. The distribution of total ACE-III and subdomain scores across all dementias were similar. There were significant differences in scores for attention, memory and fluency between Alzheimer's disease and mixed dementia, and for visuospatial and language between Alzheimer's disease–vascular dementia (p < 0.05 for all). However, despite the significant differences across these subdomains, there was a high degree of overlap between these scores (> 73%) and thus the differences are not clinically relevant. The results suggest that ACE-III is a useful tool for discriminating between dementia, MCI and controls, but it is not reliable for discriminating between dementia subtypes. Nonetheless, the ACE-III is still a reliable tool for clinicians that can assist in making a dementia diagnosis in combination with other factors at assessment. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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