The inflammatory potential of the diet in childhood is associated with cardiometabolic risk in adolescence/young adulthood in the ALSPAC birth cohort.
Purpose: This study examined the association between a Dietary Inflammatory Score adapted for children (cDIS) and Cardiometabolic Risk (CMR) score in adolescence/early adulthood in the Avon Longitudinal Study of Parents and Children (ALSPAC). Methods: The cDIS was calculated at 7, 10 and 13 years us...
| Published in: | European Journal of Nutrition Vol. 61; no. 7; pp. 3471 - 3487 |
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| Main Authors: | , , , |
| Format: | research tables/charts Journal Article |
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Springer Nature
Oct2022
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159000194&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159000194 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Oct2022 vid: 61 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 159000194 156965591 159000194 159000194 10.1007/s00394-022-02860-9 159000194 ppf: 3471 ppct: 16 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The inflammatory potential of the diet in childhood is associated with cardiometabolic risk in adolescence/young adulthood in the ALSPAC birth cohort. aug: au: Buckland, Genevieve Northstone, Kate Emmett, Pauline M. Taylor, Caroline M. affil: Centre for Academic Child Health, Bristol Medical School, University of Bristol, Canynge Hall, 39 Whatley Road, BS8 2PS, Bristol, UK sug: subj: Diet Adverse Effects Inflammation Etiology Cardiometabolic Risk Factors In Adolescence Cardiometabolic Risk Factors In Adulthood Risk Assessment Human Prospective Studies Child Adolescence Young Adult Clinical Assessment Tools Diaries Anthropometry Descriptive Statistics Multivariate Statistics Linear Regression Biological Markers Confidence Intervals Child: 6-12 years Adolescent: 13-18 years ab: Purpose: This study examined the association between a Dietary Inflammatory Score adapted for children (cDIS) and Cardiometabolic Risk (CMR) score in adolescence/early adulthood in the Avon Longitudinal Study of Parents and Children (ALSPAC). Methods: The cDIS was calculated at 7, 10 and 13 years using diet diary data. Anthropometric and biochemical data at 17 (N = 1937) and 24 (N = 1957) years were used to calculate CMR scores at each age [mean sex-specific z-scores from triacylglycerol, HDL-cholesterol, LDL-cholesterol, mean arterial blood pressure (MAP), homeostatic model assessment of insulin resistance (HOMA-IR) and fat-mass index (FMI)]. Multivariable linear regression models examined associations between cDIS at 7, 10 and 13 years and a continuous CMR z-score and individual CMR markers at 17 and 24 years. Results: In fully adjusted models, a higher cDIS (more pro-inflammatory diet) at 7 years was associated with an increase in CMR z-score at 17 years (β 0.19; 95% CI 0.03–0.35 for third versus first cDIS tertile) and at 24 years (β 0.28; 95% CI 0.11,0.44 for third versus first cDIS tertile). There was a weak association between a higher cDIS at 10 years and an increase in CMR z-score at 17 years (β 0.16; 95% CI − 0.003, 0.32 for third versus first cDIS tertile). No other clear associations were evident. FMI, MAP and HOMA-IR were the main CMR factors contributing to these associations. Conclusion: A more pro-inflammatory diet during childhood was associated with a worse cardiometabolic profile in late adolescence/early adulthood. A childhood diet abundant in nutrients with anti-inflammatory properties could help reduce development of CMR factors. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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