Dissociation of behavioral and neural responses to provocation during reactive aggression in healthy adults with high versus low externalization.
The externalizing spectrum describes a range of heterogeneous personality traits and behavioral patterns, primarily characterized by antisocial behavior, disinhibition, and substance (mis)use. In psychopathology, abnormalities in neural threat, reward responses and the impulse-control system may be...
| Publicado en: | Cognitive, Affective & Behavioral Neuroscience Vol. 22; no. 5; pp. 1130 - 1145 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Oct2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159002755&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159002755 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15307026 NA4 jtl: Cognitive, Affective & Behavioral Neuroscience issn: 15307026 maglogo: N pubinfo: dt: Oct2022 vid: 22 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 159002755 154920168 10.3758/s13415-021-00981-y 159002755 ppf: 1130 ppct: 15 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Dissociation of behavioral and neural responses to provocation during reactive aggression in healthy adults with high versus low externalization. aug: au: Konzok, Julian Henze, Gina-Isabelle Kreuzpointner, Ludwig Peter, Hannah L. Giglberger, Marina Bärtl, Christoph Massau, Claudia Kärgel, Christian Weidacker, Kathrin Schiffer, Boris Eisenbarth, Hedwig Wüst, Stefan Kudielka, Brigitte M. affil: Department of Medical Psychology, Psychological Diagnostics and Research Methodology, Institute of Psychology, University of Regensburg, Universitaetsstrasse 31, 93053, Regensburg, Germany sug: ab: The externalizing spectrum describes a range of heterogeneous personality traits and behavioral patterns, primarily characterized by antisocial behavior, disinhibition, and substance (mis)use. In psychopathology, abnormalities in neural threat, reward responses and the impulse-control system may be responsible for these externalizing symptoms. Within the non-clinical range, mechanisms remain still unclear. In this fMRI-study, 61 healthy participants (31 men) from the higher versus lower range of the non-clinical variation in externalization (31 participants with high externalization) as assessed by the subscales disinhibition and meanness of the Triarchic-Psychopathy-Measure (TriPM) performed a monetary modified Taylor-Aggression-Paradigm (mTAP). This paradigm consisted of a mock competitive-reaction-time-task played against a fictional opponent with preprogrammed win- and lose-trials. In lose-trials, participants were provoked by subtraction of an amount of money between 0 and 90 cents. As a manipulation check, provocation induced a significant rise in behavioral aggression levels linked with an increased activation in the anterior cingulate cortex (ACC). High externalization predicted reduced ACC responses to provocation. However, high externalizing participants did not behave more aggressively than the low externalization group. Additionally, the high externalizing group showed a significantly lower positive affect while no group differences emerged for negative affect. In conclusion, high externalization in the non-clinical range was related to neural alterations in regions involved in affective decision-making as well as to changes in affect but did not lead to higher behavioral aggression levels in response to the mTAP. This is in line with previous findings suggesting that aberrations at multiple levels are essential for developing externalizing disorders. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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