Structural connectivity mapping in human hippocampal-subfields using super-resolution hybrid diffusion imaging: a feasibility study.
Purpose: The goal of the current study was to introduce a new methodology that holds a promise to be used in hippocampus-aging studies using sub-millimeter super-resolution hybrid diffusion imaging (HYDI) MRI. Methods: HYDI diffusion data were acquired in two groups of older and younger healthy part...
| Publicado en: | Neuroradiology Vol. 64; no. 10; pp. 1989 - 2001 |
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| Autores principales: | , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159104045&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159104045 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00283940 NYZ jtl: Neuroradiology issn: 00283940 maglogo: N pubinfo: dt: Oct2022 vid: 64 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 159104045 156832281 159104045 159104045 10.1007/s00234-022-02968-z 159104045 ppf: 1989 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Structural connectivity mapping in human hippocampal-subfields using super-resolution hybrid diffusion imaging: a feasibility study. aug: au: Elsaid, Nahla M. H. Coupé, Pierrick Saykin, Andrew J. Wu, Yu-Chien affil: Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA sug: subj: Hippocampus Anatomy and Histology Hippocampus Anatomy and Histology Brain Mapping Methods Magnetic Resonance Imaging Methods Aging Neuroradiography Human Pilot Studies Aged Indiana Adult Comparative Studies Cerebral Cortex Aged: 65+ years Adult: 19-44 years ab: Purpose: The goal of the current study was to introduce a new methodology that holds a promise to be used in hippocampus-aging studies using sub-millimeter super-resolution hybrid diffusion imaging (HYDI) MRI. Methods: HYDI diffusion data were acquired in two groups of older and younger healthy participants recruited from the Indiana Alzheimer's Disease Research Center and community. These data were then transformed into super-resolution diffusion images before the hippocampal subfield analyses. We studied the correlation between the subjects' age and the structural connectivity involving the hippocampal subfields and the connectivity between the whole hippocampus and the cerebral cortex. Results: Structural integrity derived from the tractography streamlines between the hippocampal subfields was reduced in older than younger adults. Conclusion: The findings offered a new promising framework, and they opened avenues for future studies to explore the relationship between the structural connectivity in the hippocampal area and different types of dementia. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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