Assessment of cardiac dimensions in children diagnosed with hypertrophic cardiomyopathy.
Background: Hypertrophic cardiomyopathy (HCM) is an inherited autosomal dominant heart disease, characterized by increased left ventricular wall thickness and abnormal loading conditions. Imaging modalities are the first choice for diagnosis and risk stratification. Although heart dimensions have be...
| Publicado en: | Echocardiography Vol. 39; no. 9; pp. 1233 - 1240 |
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| Autores principales: | , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Sep2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159135606&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159135606 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07422822 GSE jtl: Echocardiography issn: 07422822 maglogo: Y pubinfo: dt: Sep2022 vid: 39 iid: 9 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 159135606 159135606 159135606 10.1111/echo.15437 159135606 ppf: 1233 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Assessment of cardiac dimensions in children diagnosed with hypertrophic cardiomyopathy. aug: au: Bakaya, Kaushiki Paracha, Waleed Schievano, Silvia Bozkurt, Selim affil: UCL Medical School, University College London, London, UK sug: subj: Cardiomyopathy, Hypertrophic Complications Cardiomyopathy, Hypertrophic Complications Ventricular Function, Left Evaluation Heart Anatomy and Histology Hemodynamics Evaluation Body Weights and Measures Human Child Adolescence Male Female United Kingdom Magnetic Resonance Imaging Heart Ventricle, Left Heart Ventricle, Right Heart Septum Comparative Studies T-Tests Nonparametric Statistics Mann-Whitney U Test Heart Rate Evaluation Diastole Ventricular Ejection Fraction Systole Cardiomyopathy, Hypertrophic Physiopathology Child: 6-12 years Adolescent: 13-18 years Male Female ab: Background: Hypertrophic cardiomyopathy (HCM) is an inherited autosomal dominant heart disease, characterized by increased left ventricular wall thickness and abnormal loading conditions. Imaging modalities are the first choice for diagnosis and risk stratification. Although heart dimensions have been characterized widely in HCM adults from cardiac imaging, there is limited information about children affected by HCM. The aim of this study is to evaluate left ventricular function and left heart dimensions in a small population of children diagnosed with HCM. Methods: A total of 16 (seven male, nine female) pediatric patients with an average age of 14.0 ± 2.5 years diagnosed with HCM at Great Ormond Street Hospital for Children were included in this study. Cardiac magnetic resonance (CMR) images were used to measure left and right ventricular dimensions, and septal and left ventricular free wall thicknesses in Simpleware ScanIP. The gender groups were compared using student t‐test or non‐parametric Mann‐Whitney U‐test depending on the sample distribution. Results: Differences in heart rate, left ventricular end‐diastolic volume and end‐diastolic volume index, left ventricular stroke volume and stroke volume index, left ventricular end‐systolic long axis length, left ventricular end‐systolic long axis length index, left ventricular end‐diastolic mid‐cavity diameter, left ventricular end‐diastolic free wall thickness, left ventricular end‐diastolic free wall thickness index, right ventricular end‐diastolic long axis length were statistically significant in males and females. Conclusion: Left ventricular wall and intraventricular septal thickness increase affecting left ventricle cavity dimensions and there may be differences in anatomical and physiological parameters in males and females affected by HCM. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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