Treatment of Pediatric Pyoderma Gangrenosum With Modified Negative Pressure Wound Therapy and Intralesional Corticosteroids: A Case Report.
BACKGROUND: Pyoderma gangrenosum (PG) is a rare ulcerative skin disease; its etiology is unknown, though it is often associated with autoimmune diseases. Pyoderma gangrenosum results in significant morbidity and exquisite pain that affects health-related quality of life. Wound healing is delayed, an...
| Publicado en: | Journal of Wound, Ostomy & Continence Nursing Vol. 49; no. 5; pp. 488 - 492 |
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| Autores principales: | , , , |
| Formato: | case study pictorial Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Sep/Oct2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159138046&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159138046 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10715754 4CQ jtl: Journal of Wound, Ostomy & Continence Nursing issn: 10715754 maglogo: N pubinfo: dt: Sep/Oct2022 vid: 49 iid: 5 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 159138046 159138046 159138046 10.1097/WON.0000000000000904 159138046 ppf: 488 ppct: 4 formats: tig: atl: Treatment of Pediatric Pyoderma Gangrenosum With Modified Negative Pressure Wound Therapy and Intralesional Corticosteroids: A Case Report. aug: au: Barker, Catherine S. Santa Lucia, Gabriella Brunette, Glenda Wine Lee, Lara affil: Catherine S. Barker, BS, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston. sug: subj: Pyoderma Gangrenosum Therapy Negative Pressure Wound Therapy Adrenal Cortex Hormones Therapeutic Use Administration, Topical Female Adolescence Colitis, Ulcerative Surgery Ileoanal Reservoir Adolescent: 13-18 years Female ab: BACKGROUND: Pyoderma gangrenosum (PG) is a rare ulcerative skin disease; its etiology is unknown, though it is often associated with autoimmune diseases. Pyoderma gangrenosum results in significant morbidity and exquisite pain that affects health-related quality of life. Wound healing is delayed, and patients often experience relapse. Pyoderma gangrenosum is susceptible to pathergy and deterioration with surgical intervention or other trauma; therefore, treatment includes atraumatic wound care, infection management, and local or systemic immunosuppression. CASE: We describe the use of modified negative pressure wound therapy (NPWT) with intralesional and topical steroids for the treatment of PG in a 15-year-old female patient with ulcerative colitis and a staged J-pouch ileoanal reconstruction. The patient and her family refused all systemic therapy due to prior steroid-associated weight gain. She was unable to tolerate conscious dressing changes, further complicating the treatment plan. Procedural interventions such as NPWT have been used previously for PG; however, they can cause wound pathergy and subsequent wound deterioration. Modified NPWT in conjunction with topical and intralesional steroids induced wound healing without producing pathergy. CONCLUSION: Timely recognition of PG is crucial to appropriate delivery of care. Modified NPWT and localized corticosteroid treatment were key to promoting wound healing in this case of pediatric PG. pubtype: Academic Journal doctype: case study pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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