Perception of clinical research among patients and healthy volunteers of clinical trials.
Purpose: Clinical research relies on data from patients and volunteers, yet the target sample size is often not achieved. Here, we assessed the perception of clinical research among clinical trial participants to improve the recruitment process for future studies. Methods: We conducted a single-cent...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 78; no. 10; pp. 1647 - 1656 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159160733&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159160733 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00316970 NP9 jtl: European Journal of Clinical Pharmacology issn: 00316970 maglogo: N pubinfo: dt: Oct2022 vid: 78 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 159160733 158203524 159160733 159160733 10.1007/s00228-022-03366-3 159160733 ppf: 1647 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Perception of clinical research among patients and healthy volunteers of clinical trials. aug: au: Bergmann, Felix Matzneller, Peter Weber, Maria Yeghiazaryan, Lusine Fuereder, Thorsten Weber, Thomas Zeitlinger, Markus affil: Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria sug: subj: Clinical Research Patient Attitudes Volunteer Workers Psychosocial Factors Clinical Trials Research Subject Recruitment Human Descriptive Research Exploratory Research Questionnaires Pharmaceutical Companies Descriptive Statistics Insurance, Health ab: Purpose: Clinical research relies on data from patients and volunteers, yet the target sample size is often not achieved. Here, we assessed the perception of clinical research among clinical trial participants to improve the recruitment process for future studies. Methods: We conducted a single-center descriptive and exploratory study of 300 current or former participants in various phase I–III clinical trials. Questionnaires were either distributed to current clinical trial participants or emailed to former subjects. Results: Subjects strongly agreed or agreed that contributing to improving medical care (> 81%), contributing to scientific research (> 79%), and trusting their treating physicians (> 77%) were motives for study participation. Among healthy volunteers, financial motives positively correlated with the number of clinical trials they had participated in (p < 0.05). Higher age positively correlated with expectation of best available treatment during study participation among patients (p < 0.05). Less than 8% of all subjects expressed "great concern" about the potential risks of sharing their personal information as part of the study. Subjects displayed "great trust" or "trust" in medical staff (86.6%) and in government research institutions (76.4%), and "very little trust" or "little trust" in pharmaceutical companies (35.4%) and health insurance companies (16.9%). Conclusion: Altruistic motives and trust in treating physicians were predominant motives for clinical trial participation. Older patients expected to receive the best available treatment during participation. Healthy volunteers who reported financial motives had participated in more clinical trials. Consistent with great trust in medical staff and government research institutions, little concern was expressed about the misuse of personal data during the trial. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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