Effect of caffeine on resting-state alpha activity across the human menstrual cycle.
Rationale: Caffeine is the most consumed stimulant worldwide, and there is great interest in understanding its neurophysiological effects. Resting-state electroencephalography (EEG) studies suggest that caffeine enhances arousal, which suppresses the spectral power of alpha frequencies associated wi...
| Publicado en: | Psychopharmacology Vol. 239; no. 10; pp. 3161 - 3171 |
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| Autores principales: | , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Oct2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159162236&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159162236 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00333158 EJD jtl: Psychopharmacology issn: 00333158 maglogo: N pubinfo: dt: Oct2022 vid: 239 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 159162236 158233783 10.1007/s00213-022-06197-3 159162236 ppf: 3161 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Effect of caffeine on resting-state alpha activity across the human menstrual cycle. aug: au: Aziz, Jasmine R. Oprea, Alexandra Bissonnette, Jenna N. Hull, Krista M. Napier, Kaitlyn Schryver, Bronwen Myles, Elizabeth M. Newman, Randy L. Perrot, Tara S. Fisher, Derek J. affil: Department of Psychology & Neuroscience, Dalhousie University, B3H 4J1, Halifax, NS, Canada sug: ab: Rationale: Caffeine is the most consumed stimulant worldwide, and there is great interest in understanding its neurophysiological effects. Resting-state electroencephalography (EEG) studies suggest that caffeine enhances arousal, which suppresses the spectral power of alpha frequencies associated with reduced alertness. However, it is unclear whether caffeine's neurophysiological effects vary across the human menstrual cycle. Objective: The objective of our study was to test whether caffeine's effect on EEG activity differs across the human menstrual cycle. Methods: Fifty-six female participants were randomly assigned to complete the experiment while in either their menstrual (n = 21), follicular (n = 19), or luteal (n = 16) phase. Each participant completed two study sessions in the same menstrual phase, approximately 1 month apart, during which they were administered either a caffeine pill (200 mg, oral) or a placebo pill in a counterbalanced order using a randomized double-blinded procedure. We measured their eyes-closed resting-state EEG approximately 30 min after pill administration and conducted a spectral power analysis at different frequency bands. Results: Caffeine reduced EEG power in the alpha1 frequency band (8–10 Hz), but only for participants who self-reported higher weekly caffeine consumption. Importantly, caffeine's effects did not differ by menstrual phase. Conclusions: We conclude that when studying caffeine's effects on resting-state EEG, participants' baseline caffeine consumption is more influential than their menstrual cycle phase. This study has important implications for the inclusion of menstruating individuals in neurophysiological studies of caffeine. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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