Computer-Aided Diagnosis for Determining Sagittal Spinal Curvatures Using Deep Learning and Radiography.

Analyzing spinal curvatures manually is time-consuming and tedious for clinicians, and intra-observer and inter-observer variability can affect manual measurements. In this study, we developed and evaluated the performance of an automated deep learning–based computer-aided diagnosis (CAD) tool for m...

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Publicado en:Journal of Digital Imaging Vol. 35; no. 4; pp. 846 - 860
Autores principales: Lee, Hyo Min, Kim, Young Jae, Cho, Je Bok, Jeon, Ji Young, Kim, Kwang Gi
Formato: algorithm diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Aug2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2022
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-022-00592-0
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        atl: Computer-Aided Diagnosis for Determining Sagittal Spinal Curvatures Using Deep Learning and Radiography.
      aug:
        au:
          Lee, Hyo Min
          Kim, Young Jae
          Cho, Je Bok
          Jeon, Ji Young
          Kim, Kwang Gi
        affil: Department of Biomedical Engineering, College of Health Science, Gachon University, Seongnam, South Korea
      sug:
        subj:
          Spinal Curvatures Radiography
          Spinal Diseases Radiography
          Diagnosis, Computer Assisted
          Deep Learning
          Algorithms Evaluation
          Predictive Value of Tests Evaluation
          Human
          Thoracic Vertebrae Pathology
          Lumbar Vertebrae Pathology
          Kyphosis Diagnosis
          Lordosis Diagnosis
          Sensitivity and Specificity
          Descriptive Statistics
          Pearson's Correlation Coefficient
          Intraclass Correlation Coefficient
          Reliability
          Intrarater Reliability
          Interrater Reliability
      ab: Analyzing spinal curvatures manually is time-consuming and tedious for clinicians, and intra-observer and inter-observer variability can affect manual measurements. In this study, we developed and evaluated the performance of an automated deep learning–based computer-aided diagnosis (CAD) tool for measuring the sagittal alignment of the spine from X-ray images. The CAD system proposed here performs two functions: deep learning–based lateral spine segmentation and automatic analysis of thoracic kyphosis and lumbar lordosis angles. We utilized 322 datasets with data augmentation for learning and fivefold cross-validation. The segmentation model was based on U-Net, which has multiple applications in medical image processing. Here, we utilized parameter equations and trigonometric functions to design spinal angle measurement algorithms. The kyphosis (T4–T12) and lordosis angle (L1–S1, L1–L5) were automatically measured to help diagnose kyphosis and lordosis. The segmentation model had precision, sensitivity, and dice similarity coefficient values of 90.53 ± 4.61%, 89.53 ± 1.8%, and 90.22 ± 0.62%, respectively. The performance of the CAD algorithm was also verified with the Pearson correlation, Bland–Altman, and intra-class correlation coefficient (ICC) analysis. The proposed angle measurement algorithm exhibited high similarity and reliability during verification. Therefore, CAD can help clinicians in reaching a diagnosis by analyzing the sagittal spinal curvatures while reducing observer-based variability and the required time or effort.
      pubtype: Academic Journal
      doctype:
        algorithm
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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