Predischarge cerebral oxygenation and psychomotor outcome in very preterm infants: is there an association?
This observational study aimed to investigate whether predischarge cerebral oxygenation (CrSO2), monitored by near-infrared spectroscopy, correlates with later psychomotor outcome in very preterm infants. Infants <32 weeks' gestation or <1500 g without evidence of major brain lesions underwent a 3-h...
| Publicado en: | European Journal of Pediatrics Vol. 181; no. 10; pp. 3711 - 3715 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Oct2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159302937&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159302937 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03406199 CR1 jtl: European Journal of Pediatrics issn: 03406199 maglogo: N pubinfo: dt: Oct2022 vid: 181 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 159302937 158352836 159302937 NLM35927381 10.1007/s00431-022-04578-6 NLM35927381 159302937 ppf: 3711 ppct: 4 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Predischarge cerebral oxygenation and psychomotor outcome in very preterm infants: is there an association? aug: au: Martini, Silvia Savini, Silvia Sansavini, Alessandra Corvaglia, Luigi affil: Neonatal Intensive Care Unit, IRCCS AOU S. Orsola, Via Massarenti 13-40138, Bologna, Italy sug: subj: Infant, Premature, Diseases Infant, Premature Infant, Very Low Birth Weight Infant Spectroscopy, Near-Infrared Fetal Growth Retardation Female Infant, Newborn Oxygen Scales Infant: 1-23 months Infant, Newborn: birth-1 month Female ab: This observational study aimed to investigate whether predischarge cerebral oxygenation (CrSO2), monitored by near-infrared spectroscopy, correlates with later psychomotor outcome in very preterm infants. Infants <32 weeks' gestation or <1500 g without evidence of major brain lesions underwent a 3-h continuous CrSO2 monitoring before hospital discharge. Psychomotor development was assessed at 6, 12, 18, and 24 months using the Griffiths Mental Developmental Scales. The developmental quotients (DQ) at each follow-up appointment were correlated with predischarge CrSO2. Significant correlations were adjusted for possible confounders. Sixty-three infants were enrolled. A significant correlation between CrSO2 and DQ was observed at 6 months ca (p=0.010), but not at later psychomotor assessments. This correlation was confirmed significant (b=0.274, p=0.038) even after the adjustment for relevant covariates. Conclusion: According to these preliminary findings, the association between predischarge CrSO2 and psychomotor development over the first 24 months in preterm infants without major brain lesions is time-limited. Hence, this parameter may not represent an effective predictor for medium-term neurodevelopment. What is Known: • Prematurity is a major risk factor for adverse neurodevelopment. • The validation of clinical tools for psychomotor outcome prediction may aid to identify high-risk preterm infants who might benefit from early interventions. What is New: • In infants without major brain lesions, predischarge CrSO2 correlates with psychomotor outcome at 6 months ca but not later, indicating a short time predictability. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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