Multiarea Brain Activation and Gait Deterioration During a Cognitive and Motor Dual Task in Individuals With Parkinson Disease.
Background and Purpose: In people with Parkinson disease (PD), gait performance deteriorating during dual-task walking has been noted in previous studies. However, the effects of different types of dual tasks on gait performance and brain activation are still unknown. The purpose of this study was t...
| Publicado en: | Journal of Neurologic Physical Therapy Vol. 46; no. 4; pp. 260 - 270 |
|---|---|
| Autores principales: | , , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Oct2022
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159375833&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159375833 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15570576 1FUT jtl: Journal of Neurologic Physical Therapy issn: 15570576 maglogo: N pubinfo: dt: Oct2022 vid: 46 iid: 4 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 159375833 159375833 159375833 10.1097/NPT.0000000000000402 159375833 ppf: 260 ppct: 10 formats: tig: atl: Multiarea Brain Activation and Gait Deterioration During a Cognitive and Motor Dual Task in Individuals With Parkinson Disease. aug: au: Liu, Yan-Ci Yang, Yea-Ru Yeh, Nai-Chen Ku, Pei-Hsin Lu, Chia-Feng Wang, Ray-Yau affil: School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan (Y.C.L.) sug: subj: Brain Physiopathology Gait Disorders, Neurologic Diagnosis Parkinson Disease Physiopathology Cognition Evaluation Motor Activity Evaluation Task Performance and Analysis Walking Evaluation Gait Analysis Human Walking Speed Prefrontal Cortex Spectrophotometry, Infrared Cross Sectional Studies Young Adult Adult Middle Age Aged Aged, 80 and Over Descriptive Statistics Power Analysis Male Female Neuropsychological Tests T-Tests Repeated Measures Multivariate Analysis of Variance Post Hoc Analysis Pearson's Correlation Coefficient Data Analysis Software Comparative Studies Hemodynamics Brain Mapping Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Background and Purpose: In people with Parkinson disease (PD), gait performance deteriorating during dual-task walking has been noted in previous studies. However, the effects of different types of dual tasks on gait performance and brain activation are still unknown. The purpose of this study was to investigate cognitive and motor dual-task walking performance on multiarea brain activity in individuals with PD. Methods: Twenty-eight participants with PD were recruited and performed single walking (SW), walking while performing a cognitive task (WCT), and walking while performing a motor task (WMT) at their self-selected speed. Gait performance including walking speed, stride length, stride time, swing cycle, temporal and spatial variability, and dual-task cost (DTC) was recorded. Brain activation of the prefrontal cortex (PFC), premotor cortex (PMC), and supplementary motor areas (SMA) were measured using functional near-infrared spectroscopy during walking. Results: Walking performance deteriorated upon performing a secondary task, especially the cognitive task. Also, a higher and more sustained activation in the PMC and SMA during WCT, as compared with the WMT and SW, in the late phase of walking was found. During WMT, however, the SMA and PMC did not show increased activation compared with during SW. Moreover, gait performance was negatively correlated with PMC and SMA activity during different walking tasks. Discussion and Conclusions: Individuals with mild to moderate PD demonstrated gait deterioration during dual-task walking, especially during WCT. The SMA and PMC were further activated in individuals with PD when performing cognitive dual-task walking. Supplemental Digital Content is Available in the Text. Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A383). pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|