Single isocenter stereotactic irradiation for multiple brain metastases: current situation and prospects.

The prognosis of patients with brain metastases has dramatically improved, and long-term tumor control and reduction of the risk of late toxicities, including neurocognitive dysfunction, are important for patient quality of life. Stereotactic irradiation for multiple brain metastases, rather than wh...

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Publicado en:Japanese Journal of Radiology Vol. 40; no. 10; pp. 987 - 995
Autores principales: Uto, Megumi, Torizuka, Daichi, Mizowaki, Takashi
Formato: review Journal Article
Publicado: Springer Nature Oct2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2022
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11604-022-01333-7
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        atl: Single isocenter stereotactic irradiation for multiple brain metastases: current situation and prospects.
      aug:
        au:
          Uto, Megumi
          Torizuka, Daichi
          Mizowaki, Takashi
        affil: Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, 54, Shogoin Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan
      sug:
        subj:
          Sexually Transmitted Diseases
          Brain Neoplasms Pathology
          Radiosurgery
          Quality of Life
          Radiation Dosage
          Particle Accelerators
          Scales
          Ferrans and Powers Quality of Life Index
      ab: The prognosis of patients with brain metastases has dramatically improved, and long-term tumor control and reduction of the risk of late toxicities, including neurocognitive dysfunction, are important for patient quality of life. Stereotactic irradiation for multiple brain metastases, rather than whole-brain radiotherapy, can result in high local control rate with low incidence of neurocognitive deterioration and leukoencephalopathy. Recent advances in radiotherapy devices, treatment-planning systems, and image-guided radiotherapy can realize single isocenter stereotactic irradiation for multiple brain metastases (SI-STI-MBM), in which only one isocenter is sufficient to treat multiple brain metastases simultaneously. SI-STI-MBM has expanded the indications for linear accelerator-based stereotactic irradiation and considerably reduced patient burden. This review summarizes the background, methods, clinical outcomes, and specific consideration points of SI-STI-MBM. In addition, the prospects of SI-STI-MBM are addressed.
      pubtype: Academic Journal
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        review
        Journal Article
      ougenre: Article
    language: English
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