Effects of Different Doses of Dex Anesthesia on Inflammatory Factors and Hemodynamics in Patients Undergoing Neurosurgery and Its Relationship with RSS Score.

The effects of different doses of dexmedetomidine (Dex) anesthesia on inflammatory factors and hemodynamics in patients undergoing neurosurgery and its relationship with RSS scores are analyzed. A total of 102 patients who received neurosurgery in our hospital from March 2021 to March 2022 are selec...

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Publicado en:BioMed Research International pp. 1 - 6
Autores principales: Lu, Qiaoling, Wu, Chengwei, Wu, Zhenhua, Wang, Xinbin, Cheng, Hao
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 10/5/2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 10/5/2022
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2022/6447407
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        atl: Effects of Different Doses of Dex Anesthesia on Inflammatory Factors and Hemodynamics in Patients Undergoing Neurosurgery and Its Relationship with RSS Score.
      aug:
        au:
          Lu, Qiaoling
          Wu, Chengwei
          Wu, Zhenhua
          Wang, Xinbin
          Cheng, Hao
        affil: Department of Anesthesiology, The Fifth Affiliated Hospital of Wenzhou Medical University, Affiliated Lishui Hospital of Zhejiang University, The Central Hospital of Zhejiang Lishui, Lishui 323000, China
      sug:
        subj:
          Imidazoles Pharmacodynamics
          Anesthesia
          Hemodynamics Evaluation
          Neurosurgery Methods
          Inflammation
          Human
          Scales
          Postoperative Care
          Sedation Evaluation
      ab: The effects of different doses of dexmedetomidine (Dex) anesthesia on inflammatory factors and hemodynamics in patients undergoing neurosurgery and its relationship with RSS scores are analyzed. A total of 102 patients who received neurosurgery in our hospital from March 2021 to March 2022 are selected. According to different intraoperative Dex dose, the enrolled patients are randomly divided into low-, medium-, and high-dose groups, 34 patients in each group. In this study, hemodynamic indexes, inflammatory factors, anesthesia effect, and the Ramsay sedation scale (RSS) score are compared in each groups. The experimental results show that in neurosurgery, compared with low-dose Dex, high-dose Dex can better maintain patients' intraoperative hemodynamic parameters and effectively inhibit postoperative inflammatory response, but postoperative awakening time is also relatively prolonged, while medium-dose Dex can effectively control patients' awakening time.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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