Comparison of the analgesic effect of inhaled lavender vs vanilla essential oil for neonatal frenotomy: a randomized clinical trial (NCT04867824).
It is necessary to treat neonatal pain because it may have short- and long-term adverse effects. Frenotomy is a painful procedure where sucking, a common strategy to relieve pain, cannot be used because the technique is performed on the tongue. In a previous randomized clinical trial, we demonstrate...
| Published in: | European Journal of Pediatrics Vol. 181; no. 11; pp. 3923 - 3930 |
|---|---|
| Main Authors: | , , , , , |
| Format: | research randomized controlled trial Journal Article |
| Published: |
Springer Nature
Nov2022
|
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159548687&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159548687 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03406199 CR1 jtl: European Journal of Pediatrics issn: 03406199 maglogo: N pubinfo: dt: Nov2022 vid: 181 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 159548687 159015939 159548687 NLM36076107 159548687 10.1007/s00431-022-04608-3 NLM36076107 159548687 ppf: 3923 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Comparison of the analgesic effect of inhaled lavender vs vanilla essential oil for neonatal frenotomy: a randomized clinical trial (NCT04867824). aug: au: Maya-Enero, Silvia Fàbregas-Mitjans, Montserrat Llufriu-Marquès, Rosa Maria Candel-Pau, Júlia Garcia-Garcia, Jordi López-Vílchez, María Ángeles affil: Department of Neonatology, Service of Pediatrics, Hospital del Mar, Parc de Salut Mar, Universitat Pompeu Fabra, Passeig Marítim 25-29, 08003, Barcelona, Spain sug: subj: Plants Lavender Essential Oils Therapeutic Use Human Analgesics Hypnotics and Sedatives Pain Etiology Sucrose Frenum (Oral) Surgery Infant, Newborn Breast Feeding Adverse Effects Female Parasympatholytics Comparative Studies Multicenter Studies Randomized Controlled Trials Evaluation Research Validation Studies Infant, Newborn: birth-1 month Female ab: It is necessary to treat neonatal pain because it may have short- and long-term adverse effects. Frenotomy is a painful procedure where sucking, a common strategy to relieve pain, cannot be used because the technique is performed on the tongue. In a previous randomized clinical trial, we demonstrated that inhaled lavender essential oil (LEO) reduced the signs of pain during neonatal frenotomy. We aimed to find out whether inhaled vanilla essential oil (VEO) is more effective in reducing pain during frenotomy than LEO. Randomized clinical trial with neonates who underwent a frenotomy for type 3 tongue-ties between May and October 2021. Pain was assessed using pre and post-procedure heart rate (HR) and oxygen saturation (SatO2), crying time, and NIPS score. Neonates were randomized into "experimental" and "control" group. In both groups, we performed swaddling, administered oral sucrose, and let the newborn suck for 2 min. We placed a gauze pad with one drop of LEO (control group) or of VEO (experimental group) under the neonate's nose for 2 min prior to and during the frenotomy. We enrolled 142 neonates (71 per group). Both groups showed similar NIPS scores (2.02 vs 2.38) and crying times (15.3 vs 18.7 s). We observed no differences in HR increase or in SatO2 decrease between both groups. We observed no side effects in either of the groups.Conclusions: We observed no appreciable difference between LEO and VEO; therefore, we cannot conclude which of them was more effective in treating pain in neonates who underwent a frenotomy.Trial Registration: This clinical trial is registered with www.Clinicaltrials: gov with NCT04867824.What Is Known: • Pain management is one of the most important goals of neonatal care as it can have long-term neurodevelopmental effects. • Lavender essential oil can help relieve pain due to its sedative, antispasmodic, and anticolic properties.What Is New: • Lavender and vanilla essential oils are safe, beneficial, easy to use, and cheap in relieving pain in neonates who undergo a frenotomy for type 3 tongue-ties. pubtype: Academic Journal doctype: research randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|