Why not? Motivations for entering a volunteer register for clinical trials during the COVID-19 pandemic.
Backgrounds: Healthy volunteers play a key role in clinical trials and it is crucial to develop recruitment strategies that capitalise on their motivations and maximise their participation. The COVID-19 pandemic has shown the importance of finding motivated healthy volunteers for the development of...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 78; no. 11; pp. 1791 - 1801 |
|---|---|
| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Nov2022
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159549281&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159549281 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00316970 NP9 jtl: European Journal of Clinical Pharmacology issn: 00316970 maglogo: N pubinfo: dt: Nov2022 vid: 78 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 159549281 159099368 159549281 159549281 10.1007/s00228-022-03385-0 159549281 ppf: 1791 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Why not? Motivations for entering a volunteer register for clinical trials during the COVID-19 pandemic. aug: au: Russo, Selena Bani, Marco Terraneo, Marco Quaglia, Valeria Nuvolati, Giampaolo Cavaliere, Rebecca Capici, Serena Cazzaniga, Marina Elena Strepparava, Maria Grazia affil: School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy sug: subj: COVID-19 Pandemic Italy COVID-19 Vaccines Clinical Trials Clinical Trial Registry Research Subjects Volunteer Workers Motivation Human Surveys Personal Satisfaction Italy Research Subject Recruitment Interviews Trust Volunteer Experiences ab: Backgrounds: Healthy volunteers play a key role in clinical trials and it is crucial to develop recruitment strategies that capitalise on their motivations and maximise their participation. The COVID-19 pandemic has shown the importance of finding motivated healthy volunteers for the development of new vaccines. Public registers represent a promising way to promote the participation of healthy volunteers in the research field, but their adoption is still limited. The current study aimed to explore the motivations of healthy volunteers to enrol in an Italian public register for clinical trials during the COVID-19 pandemic and their attitude toward participating in a phase 1 COVID-19 vaccine clinical trial. The impacts of different enrolling interview modalities (in person, by phone, by mail) on motivation, understanding of information and trust in researchers were also investigated. Methods: An online survey investigating experience with COVID-19, motivations to enrol, trust in researchers, political and healthcare authorities and pharmacological companies was presented to people applying as healthy volunteers in the public register for clinical trials at Phase 1 Unit Research Centre of ASST Monza, Italy, and considering to participate in a COVID-19 vaccine clinical trial. Data were collected in June 2021. Results: Altruistic motivations were the main driver for enrolling in the public register, while self-interested motivations were secondary. No gender differences were found. As for enrolling modalities, no differences emerged between in-person and interviews for motivation to enrol, understanding of information and trust in researchers. Email modality led to significantly lower volunteers' satisfaction and understanding of information but similar trust in research. Conclusions: This study supports the validity of different interview modalities (in person and by phone) for the enrolment of healthy volunteers for clinical trials and highlights the positive role of public registers for the recruitment procedures. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|