Impact of community health worker intervention on PrEP knowledge and use in Rakai, Uganda: A mixed methods, implementation science evaluation.

Background: Effective models of support for HIV pre-exposure prophylaxis (PrEP) are needed for populations at elevated risk. In a hyperendemic Ugandan fishing community, PrEP counseling was provided through a situated Information, Motivation, and Behavioral Skills (sIMB)-based community health worke...

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Publicado en:International Journal of STD & AIDS Vol. 33; no. 11; pp. 995 - 1005
Autores principales: Edwards, Abagail J, Pollard, Rose, Kennedy, Caitlin E, Mulamba, Jeremiah, Mbabali, Ismail, Anok, Aggrey, Kong, Xiangrong, Nakyanjo, Neema, Ddaaki, William, Nishimura, Holly, Wawer, Maria, Amico, K Rivet, Hutton, Heidi E, Nakigozi, Gertrude, Chang, Larry W
Formato: research tables/charts Journal Article
Publicado: Sage Publications Inc. Oct2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2022
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      pub: Sage Publications Inc.
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        atl: Impact of community health worker intervention on PrEP knowledge and use in Rakai, Uganda: A mixed methods, implementation science evaluation.
      aug:
        au:
          Edwards, Abagail J
          Pollard, Rose
          Kennedy, Caitlin E
          Mulamba, Jeremiah
          Mbabali, Ismail
          Anok, Aggrey
          Kong, Xiangrong
          Nakyanjo, Neema
          Ddaaki, William
          Nishimura, Holly
          Wawer, Maria
          Amico, K Rivet
          Hutton, Heidi E
          Nakigozi, Gertrude
          Chang, Larry W
        affil: Department of International Health, 25802 Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
      sug:
        subj:
          HIV Infections Drug Therapy
          Preventive Health Care Methods
          HIV Infections Prevention and Control
          Uganda
          Prospective Studies
          Community Health Workers Psychosocial Factors
          Funding Source
      ab: Background: Effective models of support for HIV pre-exposure prophylaxis (PrEP) are needed for populations at elevated risk. In a hyperendemic Ugandan fishing community, PrEP counseling was provided through a situated Information, Motivation, and Behavioral Skills (sIMB)-based community health worker (CHW) intervention. We evaluated the intervention using a mixed-methods, implementation science design.Methods: We surveyed all community members aged 15-49 through the Rakai Community Cohort Study. We used multivariable logistic regressions with generalized estimating equations to estimate the intervention's effect on PrEP knowledge and utilization. To understand intervention experiences and mechanisms, we conducted 74 qualitative interviews with 5 informant types (clients, CHWs, program staff, community leaders, health clinic staff) and analyzed data using an iterative, deductive approach. A mobile phone application provided intervention process implementation data.Results: Individuals self-reporting receipt of the CHW intervention showed significantly higher PrEP knowledge (N = 1848, PRR: 1.10, 95% CI: 1.06-1.14, p = <.0001), PrEP ever use (N = 1176, PRR: 1.77, 95% CI: 1.33-2.36, p = <.0001), and PrEP current use (N = 1176, PRR: 1.86, 95% CI: 1.22-2.82, p = 0.0039) compared to those who did not. Qualitative findings attributed positive PrEP outcomes to CHW counseling and effective use of motivational interviewing skills by CHWs. Salient themes across the RE-AIM framework included support for the CHW intervention and PrEP across clients, community, and implementers. Mobile application data demonstrated consistent delivery of the PrEP module throughout implementation.Conclusions: CHWs improved PrEP knowledge and use among clients in an HIV hyperendemic fishing community. Mixed-methods, implementation science evaluations can inform adaptation of similar PrEP implementation strategies.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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