Development and Analytical Validation of a 6-Plex Reverse Transcription Droplet Digital PCR Assay for the Absolute Quantification of Prostate Cancer Biomarkers in Circulating Tumor Cells of Patients with Metastatic Castration-Resistant Prostate Cancer.

BACKGROUND: Gene expression in circulating tumor cells (CTCs) can be used as a predictive liquid biopsy test in metastatic castration-resistant prostate cancer (mCRPC). We developed a novel 6-plex reverse transcription droplet digital PCR (RT-ddPCR) assay for the absolute quantification of 4 prostat...

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Publicado en:	Clinical Chemistry Vol. 68; no. 10; pp. 1323 - 1336
Autores principales:	Zavridou, Martha, Smilkou, Stavroula, Tserpeli, Victoria, Sfika, Aggeliki, Bournakis, Evangelos, Strati, Areti, Lianidou, Evi
Formato:	Journal Article
Publicado:	Oxford University Press / USA Oct2022
Acceso en línea:	Ver este registro en EBSCOhost