| Sumario: | Background and Purpose: Measuring patient-rated levels of pain and physical function is a standard in musculoskeletal practice. Objectively appraising change following intervention across a broader range of physical and psychosocial attributes might be possible in this population. This analysis was to determine if Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Interference (PI), Physical Function (PF), Fatigue, and Self-Efficacy for Managing Symptoms (SE) measures are responsive in musculoskeletal physical therapy patients. Methods: This study comprised 105 consecutive patients (48.3±18.8 years; 60% female). All PROMIS measures were completed at evaluation and at discharge. Change scores and effect sizes were calculated for the total sample and subgroups. Results: All measures showed significant mean T-score improvement overall. Effect sizes were moderate for PI (0.66-0.68) and PF (0.60-0.68), smaller for Fatigue and SE (both 0.38-0.42). Initial T-scores worse than published cut-off scores showed large effect sizes (≥0.80) for all four measures. Fourteen percent of patients only showed meaningful improvement in Fatigue and/or SE measures. Clinical Relevance: All 4 PROMIS measures are responsive across musculoskeletal diagnoses. Tracking changes in Fatigue and SE measures may provide clinicians with additional insight into patient response to treatment, particularly when not seeing improvements in pain complaints and or physical functioning.
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