Identifying Medicare Beneficiaries With Delirium.

Background: Each year, thousands of older adults develop delirium, a serious, preventable condition. At present, there is no well-validated method to identify patients with delirium when using Medicare claims data or other large datasets. We developed and assessed the performance of classification a...

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Publicado en:Medical Care Vol. 60; no. 11; pp. 852 - 860
Autores principales: Moura, Lidia M.V.R., Zafar, Sahar, Benson, Nicole M., Festa, Natalia, Price, Mary, Donahue, Maria A., Normand, Sharon-Lise, Newhouse, Joseph P., Blacker, Deborah, Hsu, John
Formato: research Journal Article
Publicado: Lippincott Williams & Wilkins Nov2022
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Identifying Medicare Beneficiaries With Delirium.
      aug:
        au:
          Moura, Lidia M.V.R.
          Zafar, Sahar
          Benson, Nicole M.
          Festa, Natalia
          Price, Mary
          Donahue, Maria A.
          Normand, Sharon-Lise
          Newhouse, Joseph P.
          Blacker, Deborah
          Hsu, John
        affil: Neurology
      sug:
        subj:
          Delirium Diagnosis
          Delirium Epidemiology
          Antipsychotic Agents
          Medicare
          United States
          International Classification of Diseases
          Aged
          Female
          Human
          Aged: 65+ years
          Female
      ab: Background: Each year, thousands of older adults develop delirium, a serious, preventable condition. At present, there is no well-validated method to identify patients with delirium when using Medicare claims data or other large datasets. We developed and assessed the performance of classification algorithms based on longitudinal Medicare administrative data that included International Classification of Diseases, 10th Edition diagnostic codes.Methods: Using a linked electronic health record (EHR)-Medicare claims dataset, 2 neurologists and 2 psychiatrists performed a standardized review of EHR records between 2016 and 2018 for a stratified random sample of 1002 patients among 40,690 eligible subjects. Reviewers adjudicated delirium status (reference standard) during this 3-year window using a structured protocol. We calculated the probability that each patient had delirium as a function of classification algorithms based on longitudinal Medicare claims data. We compared the performance of various algorithms against the reference standard, computing calibration-in-the-large, calibration slope, and the area-under-receiver-operating-curve using 10-fold cross-validation (CV).Results: Beneficiaries had a mean age of 75 years, were predominately female (59%), and non-Hispanic Whites (93%); a review of the EHR indicated that 6% of patients had delirium during the 3 years. Although several classification algorithms performed well, a relatively simple model containing counts of delirium-related diagnoses combined with patient age, dementia status, and receipt of antipsychotic medications had the best overall performance [CV- calibration-in-the-large <0.001, CV-slope 0.94, and CV-area under the receiver operating characteristic curve (0.88 95% confidence interval: 0.84-0.91)].Conclusions: A delirium classification model using Medicare administrative data and International Classification of Diseases, 10th Edition diagnosis codes can identify beneficiaries with delirium in large datasets.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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