Monitoring Worker Exposure to Respirable Crystalline Silica: Application for Data-driven Predictive Modeling for End-of-Shift Exposure Assessment.
In the ever-expanding complexities of the modern-day mining workplace, the continual monitoring of a safe and healthy work environment is a growing challenge. One specific workplace exposure concern is the inhalation of dust containing respirable crystalline silica (RCS) which can lead to silicosis,...
| Publicado en: | Annals of Work Exposures & Health Vol. 66; no. 8; pp. 1010 - 1022 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Oxford University Press / USA
Oct2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159695754&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159695754 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23987308 KJ1E jtl: Annals of Work Exposures & Health issn: 23987308 maglogo: N pubinfo: dt: Oct2022 vid: 66 iid: 8 pid: 622 pub: Oxford University Press / USA artinfo: ui: 159695754 159695754 159695754 10.1093/annweh/wxac040 159695754 ppf: 1010 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Monitoring Worker Exposure to Respirable Crystalline Silica: Application for Data-driven Predictive Modeling for End-of-Shift Exposure Assessment. aug: au: Wolfe, Cody Chubb, Lauren Walker, Rachel Yekich, Milan Cauda, Emanuele affil: Centers for Disease Control and Prevention (CDC), National Institute for Occupational Safety and Health (NIOSH), Pittsburgh Mining Research Division (PMRD) , 626 Cochran Mill Rd Pittsburgh, PA, 15236 USA sug: subj: Mining Adverse Effects Silicon Dioxide Adverse Effects Silicon Dioxide Analysis Occupational Exposure Evaluation Inhalation Exposure Evaluation Environmental Monitoring Methods Prediction Models Occupational Health Human Spectrophotometry, Infrared Multiple Regression Factor Analysis Pneumoconiosis Risk Factors Risk Assessment Environmental Monitoring Economics Dust Analysis ab: In the ever-expanding complexities of the modern-day mining workplace, the continual monitoring of a safe and healthy work environment is a growing challenge. One specific workplace exposure concern is the inhalation of dust containing respirable crystalline silica (RCS) which can lead to silicosis, a potentially fatal lung disease. This is a recognized and regulated health hazard, commonly found in mining. The current methodologies to monitor this type of exposure involve distributed sample collection followed by costly and relatively lengthy follow-up laboratory analysis. To address this concern, we have investigated a data-driven predictive modeling pipeline to predict the amount of silica deposition quickly and accurately on a filter within minutes of sample collection completion. This field-based silica monitoring technique involves the use of small, and easily deployable, Fourier transform infrared (FTIR) spectrometers used for data collection followed by multivariate regression methodologies including Principal Component Analysis (PCA) and Partial Least Squares (PLS). Given the complex nature of respirable dust mixtures, there is an increasing need to account for multiple variables quickly and efficiently during analysis. This analysis consists of several quality control steps including data normalization, PCA and PLS outlier detection, as well as applying correction factors based on the sampler and cassette used for sample collection. While outside the scope of this article to test, these quality control steps will allow for the acceptance of data from many different FTIR instruments and sampling types, thus increasing the overall useability of this method. Additionally, any sample analyzed through the model and validated using a secondary method can be incorporated into the training dataset creating an ever-growing, more robust predictive model. Multivariant predictive modeling has far-reaching implications given its speed, cost, and scalability compared to conventional approaches. This contribution presents the application of PCA and PLS as part of a computational pipeline approach to predict the amount of a deposited mineral of interest using FTIR data. For this specific application, we have developed the model to analyze RCS, although this process can be implemented in the analysis of any IR-active mineral, and this pipeline applied to any FTIR data. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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