Imaging characteristics and neurosurgical outcome in subjects with agenesis of the corpus callosum and interhemispheric cysts.
Purpose: To explore the relationships between clinical-radiological features and surgical outcomes in subjects with interhemispheric cysts (IHC) and corpus callosum anomalies. Methods: We reviewed the clinico-radiological and neurosurgical data of 38 patients surgically treated with endoscopic fenes...
| Published in: | Neuroradiology Vol. 64; no. 11; pp. 2163 - 2178 |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | diagnostic images research tables/charts Journal Article |
| Published: |
Springer Nature
Nov2022
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159724033&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159724033 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00283940 NYZ jtl: Neuroradiology issn: 00283940 maglogo: N pubinfo: dt: Nov2022 vid: 64 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 159724033 157300353 159724033 159724033 10.1007/s00234-022-02990-1 159724033 ppf: 2163 ppct: 15 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Imaging characteristics and neurosurgical outcome in subjects with agenesis of the corpus callosum and interhemispheric cysts. aug: au: Severino, Mariasavina Tortora, Domenico Reid, Catriona Uccella, Sara Nobili, Lino Accogli, Andrea Srour, Myriam Ramaglia, Antonia Sudhakar, Sniya Consales, Alessandro Pavanello, Marco Piatelli, Gianluca James, Greg Ravegnani, Marcello Rossi, Andrea Mankad, Kshitij affil: Neuroradiology Unit, IRCCS Istituto Giannina Gaslini, Via Gaslini 5, 16147, Genoa, Italy sug: subj: Signs and Symptoms Arachnoid Cysts Surgery Arachnoid Cysts Diagnosis Outcome Assessment Agenesis of Corpus Callosum Diagnosis Agenesis of Corpus Callosum Surgery Neuroradiography Human Endoscopy Male Shunts, Surgical After Care Child Arachnoid Cysts Pathology Body Weights and Measures Infant Child: 6-12 years Infant: 1-23 months Male ab: Purpose: To explore the relationships between clinical-radiological features and surgical outcomes in subjects with interhemispheric cysts (IHC) and corpus callosum anomalies. Methods: We reviewed the clinico-radiological and neurosurgical data of 38 patients surgically treated with endoscopic fenestration, shunting, or combined approaches from 2000 to 2018 (24 males, median age 9 years). Pre- and postoperative changes in IHC volume were calculated. Outcome assessment was based on clinico-radiological data. Group comparisons were performed using χ2, Fisher exact, Mann–Whitney U, and Kruskal–Wallis tests. Results: Median age at first surgery was 4 months (mean follow-up 8.3 years). Eighteen individuals (47.3%) required > 1 intervention due to IHC regrowth and/or shunt malfunction. Larger preoperative IHC volume (P =.008) and younger age at surgery (P =.016) were associated with cyst regrowth. At last follow-up, mean cystic volume was 307.8 cm3, with IHC volume reduction > 66% in 19/38 (50%) subjects. The neurological outcome was good in 14/38 subjects (36.8%), fair in 18/38 (47.3%), and poor in 6/38 (15.7%). There were no differences in the postoperative cyst volume with respect to either the type of first surgery or overall surgery type. Higher absolute postoperative IHC reduction was observed in subjects who underwent both IHC fenestration and shunting procedures (P <.0001). No differences in neurological outcome were found according to patient age at surgery or degree of IHC reduction. Conclusion: Endoscopic fenestration and shunting approaches are both effective but often require multiple procedures especially in younger patients. Larger IHC are more frequently complicated by cyst regrowth after surgery. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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