Speed of sound index for liver steatosis estimation: a reliability study in normal subjects.

PURPOSE Non-alcoholic fatty liver disease (NAFLD) is the most widespread type of chronic liver disease in the Western countries. Ultrasound (US) is widely used for NAFLD staging. The Resona 7 US system (Mindray Bio-Medical Electronics Co., Ltd.) includes an image optimization and speed of ultrasound...

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Publicado en:Diagnostic & Interventional Radiology Vol. 28; no. 5; pp. 418 - 428
Autores principales: Gatos, Ilias, Drazinos, Petros, Loupas, Thanasis, Yarmenitis, Spyros, Koskinas, John, Zoumpoulis, Pavlos S.
Formato: diagnostic images research tables/charts Journal Article
Publicado: Galenos Yayinevi Tic. LTD. STI Sep2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2022
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      pub: Galenos Yayinevi Tic. LTD. STI
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        atl: Speed of sound index for liver steatosis estimation: a reliability study in normal subjects.
      aug:
        au:
          Gatos, Ilias
          Drazinos, Petros
          Loupas, Thanasis
          Yarmenitis, Spyros
          Koskinas, John
          Zoumpoulis, Pavlos S.
        affil: Department of Medical Physics, University of Patras, School of Medicine, Rion, Greece
      sug:
        subj:
          Nonalcoholic Fatty Liver Disease
          Ultrasonography
          Liver
          Reproducibility of Results
          Observer Bias
          Social Support Index
          Scales
          Human
      ab: PURPOSE Non-alcoholic fatty liver disease (NAFLD) is the most widespread type of chronic liver disease in the Western countries. Ultrasound (US) is widely used for NAFLD staging. The Resona 7 US system (Mindray Bio-Medical Electronics Co., Ltd.) includes an image optimization and speed of ultrasound-related feature, Sound Speed Index (SSI). SSI is applied in a region of interest (ROI) that could potentially aid in tissue characterization. The purpose of this study is to evaluate the reliability of SSI on various examination parameters on normal subjects. METHODS Twenty normal subjects were examined by two radiologists performing SSI measurements in the liver in different ROI depths and sizes. Intraclass correlation coefficient (ICC) was calculated to measure intra- and inter-observer variability and inter-ROI variability. RESULTS For all ROIs and both radiologists, the mean inter-observer ICC was 0.62 and the mean intraobserver ICC was 0.52 and 0.79. The mean SSI values for all ROIs and examiners were in the range 1528.79-1540.16 m/s. CONCLUSION The results indicate that SSI can lead to reliable measurements on normal subjects, independent of ROI size but dependent on ROI placement. More studies processing NAFLD patients, utilizing reference methods of liver fat quantification either for reliability or correlation with SSI, should be performed to further investigate the relevance of the SSI as a potential biomarker in clinical practice for liver steatosis grading.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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