Reciprocal modulation between cigarette smoking and internet gaming disorder on participation coefficient within functional brain networks.

Many reports indicated that cigarette smoking was associated with internet gaming disorder (IGD). However, the underlying mechanism of comorbidity between smoking and IGD and whether they had interaction effects on topological organization of brain functional network are still unknown. Therefore, we...

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Publicado en:Brain Imaging & Behavior Vol. 16; no. 5; pp. 2011 - 2021
Autores principales: Qiu, Xianxin, Han, Xu, Wang, Yao, Ding, Weina, Sun, Yawen, Lei, Hao, Zhou, Yan, Lin, Fuchun
Formato: Journal Article
Publicado: Springer Nature Oct2022
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Reciprocal modulation between cigarette smoking and internet gaming disorder on participation coefficient within functional brain networks.
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          Qiu, Xianxin
          Han, Xu
          Wang, Yao
          Ding, Weina
          Sun, Yawen
          Lei, Hao
          Zhou, Yan
          Lin, Fuchun
        affil: State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, 430071, Wuhan, People's Republic of China
      sug:
      ab: Many reports indicated that cigarette smoking was associated with internet gaming disorder (IGD). However, the underlying mechanism of comorbidity between smoking and IGD and whether they had interaction effects on topological organization of brain functional network are still unknown. Therefore, we investigated the interaction between smoking and IGD in resting-state brain functional networks for 60 healthy controls, 46 smokers, 38 IGD individuals and 34 IGD comorbid with smoking participants. The modular structures of functional networks were explored and participation coefficient (Pc) was used to characterize the importance of each brain region in the communication between modules. Significant main effect of IGD was found in the left superior frontal gyrus, bilateral medial part of superior frontal gyrus and bilateral posterior cingulate gyrus with lower Pc in IGD group than in non-IGD group. Significant interaction effects between smoking and IGD were found in the left posterior orbital gyrus, right lateral orbital gyrus, left supramarginal gyrus, left middle temporal gyrus and left inferior temporal gyrus. The interaction in these brain regions was characterized by no significant difference or significantly decreased Pc in smokers or IGD individuals while significantly increased Pc in IGD comorbid with smoking group under the influence of IGD or smoking. Our findings provide valuable information underlying the neurophysiological mechanisms of smoking and IGD, and also offer a potential target for future clinical treatment of smoking and IGD comorbidity.
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    language: English
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