Automatic Segmentation and Measurement of Choroid Layer in High Myopia for OCT Imaging Using Deep Learning.

Automatic segmentation and measurement of the choroid layer is useful in studying of related fundus diseases, such as diabetic retinopathy and high myopia. However, most algorithms are not helpful for choroid layer segmentation due to its blurred boundaries and complex gradients. Therefore, this pap...

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Publicado en:Journal of Digital Imaging Vol. 35; no. 5; pp. 1153 - 1164
Autores principales: Xu, Xiangcong, Wang, Xuehua, Lin, Jingyi, Xiong, Honglian, Wang, Mingyi, Tan, Haishu, Xiong, Ke, Han, Dingan
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Oct2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2022
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      pub: Springer Nature
      place: New York, New York
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        atl: Automatic Segmentation and Measurement of Choroid Layer in High Myopia for OCT Imaging Using Deep Learning.
      aug:
        au:
          Xu, Xiangcong
          Wang, Xuehua
          Lin, Jingyi
          Xiong, Honglian
          Wang, Mingyi
          Tan, Haishu
          Xiong, Ke
          Han, Dingan
        affil: School of Physics and Optoelectronic Engineering, Foshan University, Foshan, Guangdong, China
      sug:
        subj:
          Myopia Pathology
          Uvea Pathology
          Tomography, Optical Coherence Methods
          Deep Learning
          Automation
          Radiographic Image Enhancement Methods
          Neural Networks (Computer)
          Uvea Radiography
          Human
          Algorithms
          Experimental Studies
          Descriptive Statistics
          Uvea Anatomy and Histology
      ab: Automatic segmentation and measurement of the choroid layer is useful in studying of related fundus diseases, such as diabetic retinopathy and high myopia. However, most algorithms are not helpful for choroid layer segmentation due to its blurred boundaries and complex gradients. Therefore, this paper aimed to propose a novel choroid segmentation method that combines image enhancement and attention-based dense (AD) U-Net network. The choroidal images obtained from optical coherence tomography (OCT) are pre-enhanced by algorithms that include flattening, filtering, and exponential and linear enhancement to reduce choroid-independent information. Experimental results obtained from 800 OCT B-scans of the choroid layers from both normal eyes and high myopia showed that image enhancement significantly increased the performance of ADU-Net, with an AUC of 99.51% and a DSC of 97.91%. The accuracy of segmentation using the ADU-Net method with image enhancement is superior to that of the existing networks. In addition, we describe some algorithms that can measure automatically choroidal foveal thickness and the volume of adjacent areas. Statistical analyses of the choroidal parameters variation indicated that compared with normal eyes, high myopia has a reduction of 86.3% of the choroidal foveal thickness and 90% of the adjacent volume. It proved that high myopia is likely to cause choroid layer attenuation. These algorithms would have wide application in the diagnosis and precaution of related fundus lesions caused by choroid thinning from high myopia in future studies.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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