Segmenting Skin Biopsy Images with Coarse and Sparse Annotations using U-Net.

The number of melanoma diagnoses has increased dramatically over the past three decades, outpacing almost all other cancers. Nearly 1 in 4 skin biopsies is of melanocytic lesions, highlighting the clinical and public health importance of correct diagnosis. Deep learning image analysis methods may im...

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Publicado en:Journal of Digital Imaging Vol. 35; no. 5; pp. 1238 - 1250
Autores principales: Nofallah, Shima, Mokhtari, Mojgan, Wu, Wenjun, Mehta, Sachin, Knezevich, Stevan, May, Caitlin J., Chang, Oliver H., Lee, Annie C., Elmore, Joann G., Shapiro, Linda G.
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Oct2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2022
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-022-00641-8
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        atl: Segmenting Skin Biopsy Images with Coarse and Sparse Annotations using U-Net.
      aug:
        au:
          Nofallah, Shima
          Mokhtari, Mojgan
          Wu, Wenjun
          Mehta, Sachin
          Knezevich, Stevan
          May, Caitlin J.
          Chang, Oliver H.
          Lee, Annie C.
          Elmore, Joann G.
          Shapiro, Linda G.
        affil: University of Washington, 98195, Seattle, WA, USA
      sug:
        subj:
          Biopsy Methods
          Melanoma Diagnosis
          Deep Learning
          Melanoma Prognosis
          Microscopy, Virtual
          Image Processing, Computer Assisted Methods
          Human
          Semantics
          Public Health
          Epidermis
          Dermis
          Magnetic Resonance Imaging
      ab: The number of melanoma diagnoses has increased dramatically over the past three decades, outpacing almost all other cancers. Nearly 1 in 4 skin biopsies is of melanocytic lesions, highlighting the clinical and public health importance of correct diagnosis. Deep learning image analysis methods may improve and complement current diagnostic and prognostic capabilities. The histologic evaluation of melanocytic lesions, including melanoma and its precursors, involves determining whether the melanocytic population involves the epidermis, dermis, or both. Semantic segmentation of clinically important structures in skin biopsies is a crucial step towards an accurate diagnosis. While training a segmentation model requires ground-truth labels, annotation of large images is a labor-intensive task. This issue becomes especially pronounced in a medical image dataset in which expert annotation is the gold standard. In this paper, we propose a two-stage segmentation pipeline using coarse and sparse annotations on a small region of the whole slide image as the training set. Segmentation results on whole slide images show promising performance for the proposed pipeline.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
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        Journal Article
      ougenre: Article
    language: English
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