Development and validation of a machine learning algorithm–based risk prediction model of pressure injury in the intensive care unit.

The study aimed to establish a machine learning–based scoring nomogram for early recognition of likely pressure injuries in an intensive care unit (ICU) using large‐scale clinical data. A retrospective cohort study design was employed to develop and validate a top‐performing clinical feature panel a...

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Publicado en:International Wound Journal Vol. 19; no. 7; pp. 1637 - 1650
Autores principales: Xu, Jie, Chen, Danxiang, Deng, Xiaofang, Pan, Xiaoyun, Chen, Yu, Zhuang, Xiaoming, Sun, Caixia
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Nov2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2022
      vid: 19
      iid: 7
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/iwj.13764
        159936181
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        atl: Development and validation of a machine learning algorithm–based risk prediction model of pressure injury in the intensive care unit.
      aug:
        au:
          Xu, Jie
          Chen, Danxiang
          Deng, Xiaofang
          Pan, Xiaoyun
          Chen, Yu
          Zhuang, Xiaoming
          Sun, Caixia
        affil: Department of Thoracic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
      sug:
        subj:
          Pressure Ulcer Prognosis
          Critically Ill Patients
          Machine Learning
          Risk Assessment
          Prediction Models
          Electronic Health Records
          Instrument Validation
          Instrument Construction
          Early Diagnosis
          Human
          Nonexperimental Studies
          Retrospective Design
          Logistic Regression
          Braden Scale for Predicting Pressure Sore Risk
          Scales
          Funding Source
          ROC Curve
          Sensitivity and Specificity
          Validation Studies
      ab: The study aimed to establish a machine learning–based scoring nomogram for early recognition of likely pressure injuries in an intensive care unit (ICU) using large‐scale clinical data. A retrospective cohort study design was employed to develop and validate a top‐performing clinical feature panel accessibly in the electronic medical records (EMRs), which was in the mode of a quantifiable nomogram. Clinical factors regarding demographics, admission cause, clinical laboratory index, medical history and nursing scales were extracted as risk candidates. The performance improvement was based on the application of the machine learning technique, comprising logistic regression, decision tree and random forest algorithm with five‐fold cross‐validation (CV) technique. The comprehensive assessment of sensitivity, specificity and the area under the receiver operating characteristic curve (AUROC) was considered in the evaluation of predictive performance. The receiver operating characteristic curves revealed the top performance for the logistic regression model in respect to machine learning improvement, achieving the highest sensitivity and AUC among three types of classifiers. Compared against the 23‐point Braden scale routinely recorded online, an incorporated nomogram of logistic regression model and Braden scale achieved the best performance with an AUC of 0.87 ± 0.07 and 0.84 ± 0.05 in training and test cohort, respectively. Our findings suggest that the machine learning technique potentiated the limited predictive validity of routinely recorded clinical data on pressure injury development during ICU hospitalisation. Easily accessible electronic records held the potentials to substitute the traditional Braden score in the prediction of pressure injury in intensive care unit. Preoperative prediction of pressure injury facilitates the exemption from the severe consequences.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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