Longitudinal maturation of resting state networks: Relevance to sustained attention and attention deficit/hyperactivity disorder.
The transition from childhood to adolescence involves important neural function, cognition, and behavior changes. However, the links between maturing brain function and sustained attention over this period could be better understood. This study examined typical changes in network functional connecti...
| Publicado en: | Cognitive, Affective & Behavioral Neuroscience Vol. 22; no. 6; pp. 1432 - 1447 |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Dec2022
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=159974038&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 159974038 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15307026 NA4 jtl: Cognitive, Affective & Behavioral Neuroscience issn: 15307026 maglogo: N pubinfo: dt: Dec2022 vid: 22 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 159974038 157322346 10.3758/s13415-022-01017-9 159974038 ppf: 1432 ppct: 15 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Longitudinal maturation of resting state networks: Relevance to sustained attention and attention deficit/hyperactivity disorder. aug: au: Thomson, Phoebe Malpas, Charles B. Vijayakumar, Nandita Johnson, Katherine A. Anderson, Vicki Efron, Daryl Hazell, Philip Silk, Timothy J. affil: Department of Paediatrics, The University of Melbourne, Melbourne, Australia sug: ab: The transition from childhood to adolescence involves important neural function, cognition, and behavior changes. However, the links between maturing brain function and sustained attention over this period could be better understood. This study examined typical changes in network functional connectivity over childhood to adolescence, developmental differences in attention deficit/hyperactivity disorder (ADHD), and how functional connectivity might underpin variability in sustained attention development in a longitudinal sample. A total of 398 resting state scans were collected from 173 children and adolescents (88 ADHD, 85 control) at up to three timepoints across ages 9-14 years. The effects of age, sex, and diagnostic group on changes in network functional connectivity were assessed, followed by relationships between functional connectivity and sustained attention development using linear mixed effects modelling. The ADHD group displayed greater decreases in functional connectivity between salience and visual networks compared with controls. Lower childhood functional connectivity between the frontoparietal and several brain networks was associated with more rapid sustained attention development, whereas frontoparietal to dorsal attention network connectivity related to attention trajectories in children with ADHD alone. Brain network segregation may increase into adolescence as predicted by key developmental theories; however, participants with ADHD demonstrated altered developmental trajectories between salience and visual networks. The segregation of the frontoparietal network from other brain networks may be a mechanism supporting sustained attention development. Frontoparietal to dorsal attention connectivity can be a focus for further work in ADHD. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|