Neuroendocrine hepatic metastatic disease: the surgeon's perspective.
Neuroendocrine tumors are a rare subset of tumors that are increasing in incidence over the last 4 decades. These tumors occur along the gastrointestinal tract and bronchopulmonary tree and frequently metastasize. Up to 90% of patients with gastroenteropancreatic neuroendocrine tumors develop liver...
| Publicado en: | Abdominal Radiology Vol. 47; no. 12; pp. 4073 - 4081 |
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| Autores principales: | , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Dec2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=160002333&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 160002333 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Dec2022 vid: 47 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 160002333 156549363 10.1007/s00261-022-03515-3 160002333 ppf: 4073 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Neuroendocrine hepatic metastatic disease: the surgeon's perspective. aug: au: Concors, Seth J. Maxwell, Jessica E. affil: Division of Surgery, Department of Surgical Oncology, MD Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, TX, USA sug: ab: Neuroendocrine tumors are a rare subset of tumors that are increasing in incidence over the last 4 decades. These tumors occur along the gastrointestinal tract and bronchopulmonary tree and frequently metastasize. Up to 90% of patients with gastroenteropancreatic neuroendocrine tumors develop liver metastases (NeLM) during their clinical course. The development of NeLM and their appropriate management has a profound impact on patient morbidity and mortality. Workup of NeLM involves biopsy to define tumor grade, cross-sectional imaging to delineate the distribution and number of metastases, and hormonal studies to determine tumor functionality. Depending on these three factors, a combination of cytoreductive surgery, liver-directed therapies, and medical management—with cytostatic and cytotoxic chemotherapies, is utilized. The multidisciplinary management of patients with NeLM should carefully consider all these factors. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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